Twenty nine promising candidate bread wheat lines of National Uniform Wheat Yield Trial, 2004-05 were evaluated against stripe and leaf rust at multilocations in different agro-ecological zones of the country presenting hot spots for leaf and yellow rust along with artificial inoculation with prevalent pathotypes. These candidate lines were undergoing mandatory testing to develop varieties for irrigated and rainfed areas of Pakistan. Out of these 29 candidate lines, 9 were common to NUWYT 2003-04 and 2004-05. Three candidate lines namely, V-00125, 99B2278, 99B4012 from seeding date were found resistant to both leaf and yellow rusts and showed desirable Relative Resistance Index (RRI) during 2003-04 and 2004-05. In addition, two of these lines, 7-03 and RWM-9313 from seeding date were also found resistant to yellow and leaf rust, respectively. Out of remaining 20 candidate lines, 8 (4 from seeding date, 4 from rainfed) showed desirable RRI for both rusts in 2004-05. These lines will remain in NUWYT 2005-06 for further evaluation.