This study was conducted to examine the trends in wholesale prices of onion and potato in the major markets (Lahore, Hyderabad, Peshawar and Quetta) of Pakistan. Time series data about annual average wholesale prices of onion and potato were collected from 1981-82 to 2011-2012. Major findings of the study revealed that wholesale prices of onion and potato were increased with time. Results revealed that wholesale prices of onion in major markets namely Lahore, Hyderabad, Peshawar and Quetta were increased @ 8.97%, 8.82%, 8.53% and 8.88% per annum, respectively. Similarly, those of potato were increased @ 8.42%, in Lahore; 7.73%, Hyderabad; 8.21%, Peshawar and 7.58%, Quetta market. The increasing prices of these two essential household items will be difficult to manage by the consumers. Hence, the government has to make some measures, rules and regulations regarding control of prices.