Articles
265 open-access articles · page 5 of 14
ArticlesMetabolic potential of Azotobacter alginate producers and sustainable alternatives for alginate extraction
Simiat O. Jimoh, Faizah R. Adebowale, Kifayat O. Asafa-Adedimeji, Ramat B. Badmos-Oladapo, Taiwo A. Sorunke
This research aimed to assess the metabolic activities of Azotobacter vinelandii DT1 strain by assaying its alginate synthesizing enzymes and modifying genes, synthesize alginate from the agricultural residues, and eradicate the pathogenicity and risk as…
1 Jun 2024- Articles
Plant growth-promoting rhizobacteria (PGPR): selective screening and characterization of drought-tolerant bacteria isolated from drought-prone soils
Osama M. Ghanem, Nehal Kamal, Alaa F. Said
Plant growth promoting rhizobacteria (PGPR) have evolved to thrive in challenging environments and provide the plants with defense against the harmful impacts of the environmental stressors. The present study aimed to isolate, screen, and identify PGPB o…
1 Jun 2024 - Articles
A review on drug resistance patho-mechanisms in ESKAPE bacterial pathogens
Apoorva Jain, Ajay Kumar Oli, Sughosh Kulkarni, Raghavendra D. Kulkarni, Kelmani Chandrakanth
The escalating incidence of nosocomial infections stemming from ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) bacterial pathogens presents a formidable…
1 Jun 2024 - Articles
The antagonistic potential of Trichoderma harzianum against barley leaf-stripe disease
Sherin P. Mekhail, Marwa S. Fouad
Drechslera graminea is the causal agent of leaf-stripe disease in barley leading to substantial crop losses. The current work aimed to investigate the antagonistic activity of Trichoderma harzianum against D. graminea. Pathogen was isolated from the natu…
1 Apr 2024 - Articles
Bacterial diversity associated with urinary tract infections in humans
Sharma S, Gupta V, Yadav M, Sain D, Rahi R.K, Neelam D.K
The present study aimed to evaluate the concepts of epidemiology, uropathogenic, diagnosis, prevention, and treatment of urinary tract infections (UTI) in humans. One of the most frequent infections that affect people is UTIs. During childhood they are e…
1 Apr 2024 - Review
From gut to brain: Deciphering the impact of gut microbiota on neurological health
Gopinath R, Arundadhi M, Dhanasezhian A, Thangam G. Sucila
The Gut-Brain Axis is a complex and fascinating concept elucidating the two-way communication between gut microbiota and the central nervous system, encompassing diverse mechanisms with profound implications on neurological health. Situated in the gastro…
1 Apr 2024 - Articles
Evaluation of genetic diversity of some Zucchini yellow mosaic virus-infected cucurbits based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, inter simple sequence repeat and start codon targeted molecular tools
Shrouk E.E. Farg, Shafik D. Ibrahim, Samir Mahgoub, Atef S. Sadik, Mamdouh H. Abdel-Ghaffar
The aim of this study was to evaluate the genetic diversity of some Zucchini yellow mosaic virus (ZYMV)-infected cucurbits compared to the healthy plants based on three molecular tools. When sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-…
1 Apr 2024 - Articles
Evaluation of the antioxidant and antimicrobial activities of the spent coffee extracts and their applications as natural food preservatives of chicken fillets
Ghadir A. El-Chaghaby, Heba A. Shehta, Sayed Rashad, El-Shaimaa A. Rawash, Heba R. Eid
The present study aimed at evaluating the phytochemical composition, antioxidant, and antimicrobial potentials of spent coffee extracts (SCE) to use these extracts as natural preservatives of food. The effectiveness of SCE in postponing the oxidation and…
1 Feb 2024 - Articles
Association of multiple mutations in NS5A and NS5B genes and resistance to direct-acting antivirals in chronically infected Egyptian patients with Hepatitis C virus Genotype 4a
Gehad M. Mohamed, Ahmed B. Barakat, Marwa M. Gado, Fatma M. Abdallah
Approximately 71 million people worldwide are supposed to have chronic hepatitis C virus (CHCV). New direct-acting antiviral (DAA) medications have been used, which helped successfully in complete treatment of CHCV and achieved a sustained virological re…
1 Feb 2024 - Articles
Potentials of the marine microbial enzymes in therapeutics
Syeda Sadaf Wajahat
About 70 % of the surface of Earth is covered with oceans and hosts an enormous variety of environmental, biological, and chemical standings. The marine environment consists of a comprehensive range of animals, plants, and microorganisms, which have sev…
1 Feb 2024 - Articles
In-vitro investigation of biofilm-specific resistance and virulence of biofilm-forming uropathogenic Escherichia coli
Sara A. Alshaikh, Tarek El-Banna, Fatma Sonbol, Mahmoud H. Farghali
Uropathogenic Escherichia coli (UPEC) is the primary etiologic agent of urinary tract infections (UTIs). This study aimed to investigate the difference in antimicrobial susceptibility of UPEC isolates in the planktonic and biofilm states. Important viru…
1 Feb 2024 - Review
Recent advances in vulvovaginal Candidiasis research: A narrative review
Debasmita Dubey, Gopal Krishna Purohit, Shakti Rath, Sushree Swagatika Subhadarshini, Rajashree Panigrahi
Vulvovaginal Candidiasis (VVC) is a significant public health concern, and current article focuses primarily on understanding this infection's molecular processes. The hosts defence mechanisms and their dysregulation, such as the innate immune response and the…
1 Dec 2023DOI 10.21608/nrmj.2023.325275 - Research Article
Pseudomonas syringae pv. tomato and severity of bacterial speck disease on tomato plants in Egypt
Mahmoud Abou-Alhmd Soliman
Tomato is one of the most widespread vegetable crops in Egypt, which has a wide variation of cultivars. Tomato bacterial speck caused by Pseudomonas syringae pv. tomato is one of the most important tomato bacterial diseases. This study aimed to isolating and i…
1 Dec 2023DOI 10.21608/nrmj.2023.326365 - Review
Complex ecological approach to cystic fibrosis respiratory infections
Dmitriy V. Alekseev, Artem V. Lyamin, Karim A. Kayumov
Cystic fibrosis (CF) is one of the most common genetic disorders; resulting in a wide variety of complications, including respiratory infections. Such infections are often ineffectively treated within the framework of a classical paradigm of the infectious pro…
1 Dec 2023DOI 10.21608/nrmj.2023.327188 - Research Article
Quantification of thermo-halotolerant alkaline protease activity derived from Bacillus licheniformis strains isolated from extreme environments in Morocco
Taha Chouati, Ounayssa Ayadi, Mohammed Ajdig, Lahcen Ouchari, Bahia Rached, Jamila El Alami et al.
Proteases; especially alkaline proteases, constitute the most used group of enzymes in industry. The wide scope of their application requires varying properties; most commonly stability throughout the conditional changes that would occur during the various ind…
1 Dec 2023DOI 10.21608/nrmj.2023.325660 - Research Article
The antibiofilm activity of purified and characterized mannan from Saccharomyces cerevisiae against multidrug-resistant Escherichia coli
Naam Fadhil Abbas Al-Helli, Jehan Abdul Sattar Salman
Biofilm formation by Escherichia coli presents a major challenge in the clinical settings, resulting in persistent infections and treatment failures. These bacterial communities, protected by a matrix, resist antibiotics and immune responses, thus causing a pr…
1 Dec 2023DOI 10.21608/nrmj.2023.330426 - Research Article
Antifungal activity of essential oils emulsions, their bioactive compounds, and biological control of Fusarium wilt of Majorana hortensis
Ali, A.A.M, Hassanin, M.M.H, Abdel-Rahman, T.F.M et al.
This investigation was conducted to evaluate the activity of some essential oils emulsions and a biocide (Bio-Cure F) for controlling Fusarium wilt disease of marjoram (Majorana hortensis) caused by Fusarium oxysporum. The fungal filtrate of F. oxysporum isola…
1 Oct 2023DOI 10.21608/nrmj.2023.318807 - Review
Chronic infection: as an ecological model for emergence of the chronic obstructive pulmonary disease
Dmitriy V. Alekseev, Artem V. Lyamin, Karim A. Kayumov
Chronic infections; emerging as complications of some primary diseases, can hardly be considered as classical infectious processes. Such infections may be caused by the nontraditional pathogenic bacteria; as in the cases of cystic fibrosis; chronic obstructive…
1 Oct 2023DOI 10.21608/nrmj.2023.319451 - Review
Microbial contamination of cosmetics and the pharmaceutical products, and their preservation strategies: A comprehensive review
Souvik Roy, Saheli Majumder, Aniket Deb, Lopamudra Choudhury
A brief discussion of the numerous types of microbial contamination of the pharmaceutical and cosmetic items and their corresponding effects is attempted in this study. The pharmaceutical and cosmetic products are particularly vulnerable to microbial contamina…
1 Oct 2023DOI 10.21608/nrmj.2023.317346 - Review
The CRISPR/Cas system: Gene Editing by bacterial defense
Amira H. El-Ashry
The most precise, effective, and widely used tool for editing the genome is currently the clustered regularly interspaced short palindromic repeat (CRISPR), which represents the prokaryotes adaptive immune defense. The CRISPR/Cas-9 genome editing system relies…
1 Oct 2023DOI 10.21608/nrmj.2023.317036