Articles

Piceatannol Inhibits Akt Activation, Induces G2/M Phase Arrest and Mitochondrial Apoptosis and Augments Cisplatin Efficacy in U2OS Osteosarcoma Cells

Zijuan Li, Rong Ma, Muhammad Khan, Chenchen Liu, Xiaolin Cui, Yongming Li

Piceatannol (3,3′,4,5′-tetrahydroxy-trans-stilbene), a naturally occurring analog of resveratrol has been shown to exhibit anticancer activity in various human cancer cells. However, the anticancer mechanism of piceatannol is not well studied. In t…

Piceatannol Inhibits Akt Activation, Induces G2/M Phase Arrest and Mitochondrial Apoptosis and Augments Cisplatin Efficacy in U2OS Osteosarcoma Cells

Piceatannol (3,3′,4,5′-tetrahydroxy-trans-stilbene), a naturally occurring analog of resveratrol has been shown to exhibit anticancer activity in various human cancer cells. However, the anticancer mechanism of piceatannol is not well studied. In the meantime,…

Efficacy of Mixture of Pesticides on the Mortality and Energy Reserves of a Stored Grain Pest Trogoderma granarium Everts

Tanzeela Riaz, Farah Rauf Shakoori, Hareem Mansoor, Sana Khan, Mushtaq A. Saleem

Trogoderma granarium has become one of the most destructive insect pests of many amylaceous stored products. Its control has become difficult due to the emergence of resistance against almost all the known insecticides and fumigants. The development of resista…

Molecular Detection of Hepatitis E Virus in Layer Chickens: A Possible Public Health Risk in Pakistan

Tahir Iqbal, Umer Rashid, Naveed Shahzad, Amber Afroz, Muhammad Faheem Malik, Muhammad Idrees

Avian Hepatitis E Virus (aHEV) is a single-stranded positive-sense RNA virus causing hepatitis-splenomegaly syndrome (HSS) in chickens. To the best of our knowledge the circulation of aHEV in chicken has not been studied in Pakistan so far. Therefore…

Effects of Graded Levels of Betaine Supplementation on Growth Performance and Intestinal Morphology in Indigenous Young Yellow Feather Broilers

Chen-Yu Sun, Wen-Chao Liu, Mei Xiao, Zhi-Hui Zhao, Li-Long An

This 28-d feeding trial was conducted to evaluate the effects of dietary supplementation with different levels of betaine on growth performance and intestinal morphology in Chinese indigenous young yellow feather broilers. A total of 360 male, one-d-old Huaixi…

Production of Antibodies against Hepatitis C Virus Envelope Glycoprotein E2- A Potential Vaccine Against HCV Infection

Gul Afshan, Soumble Zulfiqar, Sumaira Mehboob, Muhammad Tahir Javed Khan, Abdul Rauf Shakoori

Currently a number of vaccines are under development against hepatitis C, though an effective hepatitis C vaccine is yet to come. The present study is focused on the development of recombinant vaccine against HCV by utilizing HCV3a envelope glycoprotein E2. HC…

Impact of Inclusion Dried Sugar Beet Pulp in Ruminant’s Ration on Rumen Parameters in vitro

Adel E.M. Mahmoud, AdamCieślak, Paulina Szulc, Anna Łukomska, Małgorzata Szumacher-Strabel

The purpose of this study was to determine effect of partial or complete replacement of corn grains by dried sugar beet pulp on rumen parameters. The yellow corn was substituted by dried sugar beet pulp at 25 (D1), 50 (D2), 75 (D3), and 100% (D4). Results of c…

Protective Effect of Quercetin Treatment against Cadmium-Induced Oxidative Stress in a Male Rat Model

Nouf Alharbi, Mai Elobeid, Promy Virk

The present study investigates the ameliorative effect of quercetin against cadmium-induced toxicity and oxidative stress in a male Sparaque Dawley rat model. There were four experimental groups with 6 rats in each: Group I control orally received normal salin…

Molecular Identification and Characterization of Fruit Flies of Genus Bactrocera (Diptera: Tephritidae) in Pakistan

Jam Nazeer Ahmad, Taiba Sharif, Samina J.N. Ahmad, Sumaira Maqsood, Fariha Zafar

 Molecular identification and characterization of tephritid fruit flies (Diptera: Tephritidae), Bactrocera zonata, Bactrocera dorsalis and Bactrocera cucurbitae was done in Punjab, Pakistan through PCR analysis using mitochondrial cytochrome oxidase I (CO…

Trends in Nutrient Status and Gas Production during the Decomposition of Poultry Manure

Qiuxia Lei, Haixia Han, Jinbo Gao, Yan Zhou, Wei Liu, Chunlei Wang et al.

To develop the effective methods for the innocuous treatment of the poultry manure, this study explored the efficiency of bacteria in decomposing the poultry manure through testing the variation of gas production and nitrogen(N), phosphorus (P), potassium(K)in…

Temporal Fluctuations in the Population of Citrus Nematode (Tylenchulus semipenetrans) in the Pothowar Region of Pakistan

Muhammad Saeed, Tariq Mukhtar, Malik Abdul Rehman

The study of the population dynamics of citrus nematode (Tylenchulus semipenetrans) in a production area is required for the assessment of damaging potential of the nematode to citrus, identification of key factors that influence population densities, and to d…

Dietary Formic Acid and Vitamin D3 as Growth Effective Supplement for Grass Carp Fingerlings

Laiba Shafique, Muhammad Afzal, Syed Zakir Hussain Shah, Mahroze Fatima, Huma Naz, Saif ur Rehman et al.

The present research was carried out to evaluate the effectiveness of dietary formic acid and vitamin D3 on growth performance and muscle proximate analyses of grass carp (Ctenopharyngodon idella). Four experimental diets viz. FD1, FD2, FD3 and FD4 having form…

Rearing of Catfish, Rita rita with Live and Prepared Feeds in Cemented Cisterns

S. Jalbani, N.T. Narejo, P. Khan

 The rearing of catfish, Rita rita with live and prepared feeds in cemented cisterns was initiated for 90 days. The juveniles of experimental fish with mean initial body weight 6.40 ± 1.6 g were procure from local fishing community of River Indus n…

Effect of UV Irradiation of Aspergillus niger on the Production of Xylanase in the Presence of Wheat Bran as Carbon Source

Muhammad Suleman, Abu ul Hassan Faiz, Muhammad Shahbaz, Ayesha Riaz

The present study was conducted to find out the effect of UV irradiation of Aspergillus niger at different concentrations of wheat bran as carbon source (2.5, 3.0, and 3.5 %) on the production of xylanase. Submerged fermentation was carried out in 500 ml Erlen…

Effects of Rearing Interlude and Grafting Technique on Honeybee Apis mellifera L. Queen under Field Conditions

Muhammad Khalid Rafique, Rashid Mahmood, Ziyad Abdul Qadir, Imran Bodlah, Farid AsifShaheen

The proposed research work was conducted at Honeybee Research Institute of National Agricultural Research Centre, Islamabad on Apis mellifera Lingustica honeybee colonies during the spring months of March-April 2017. The effects of four larval grafting techniq…

Population Status and Research Progress of Père David’s Deer (Elaphurus davidianus) in China

Huaisheng Zhang, Pengfei Li, Huajun Wen, Guangming Tian, Hui Chen, Lu Zhang et al.

The Milu has been called Père David’s deer (Elaphurus davidianus). It is a unique species in China, which has been extinct in China for nearly 200 years. In 1980, the Milu was reintroduced into China and has now become a first-class protected anim…

Regulation of Visual Sensitivity Responses in Locusts Stimulated by Different Spectral Lights

Qihang Liu, Yueli Jiang, Jin Miao, Zhongjun Gong, Tong Li, Yun Duan et al.

The locusts are causing significant damage to crops, around the globe. To avoid ecological pollution caused by the use of pesticides to control locusts, alternative methods such as photo-induced traps are elusive. In this report we investigated locusts visual…

Protective Effects of Xingnao Enema on Blood-brain Barrier Disruption in a Rat Model of Intracerebral Hemorrhage

Kun Wang, Yinglin Cui, Xu Zhao, Changjiang Hu

Xingnao enema (XN) has been commonly used to treat intracerebral hemorrhage (ICH) in China with good therapeutic effect. As very little is known about the mechanism of action of XN, the purpose of this project was to investigate the neuroprotective effect of X…

Development of 17 Novel Cross-Species Microsatellite Markers for Dabry’s Sturgeon (Acipenser dabryanus) from Chinese Sturgeon (Acipenser sinensis) via Next-Generation Sequencing

Yacheng Hu, Xueqing Liu, Jing Yang, Kan Xiao, Binzhong Wang, Hejun Du

In this study, we report 17 novel cross-species microsatellite markers for Dabry’s sturgeon via next-generation sequencing from Chinese sturgeon (Acipenser sinensis). The 17 microsatellites were polymorphic with 3 to 6 alleles per locus and the total num…

Effect of Vitamin E Supplementation on Humoral Immunity Following the Administration of Enterotoxaemia Vaccine in Goats

Mumtaz Ali Khan, Sher Bahadar Khan, Shakoor Ahmad, Irshad Ahmad, Ikramul Haq, Kashif Prince et al.

This study was conducted to evaluate and compare the effects of vitamin E supplementation on humoral immunity against Clostridium perfringens type D epsilon toxin in goats to sort out better immunogenic approach. This study was conducted on total of 36 healthy…