Articles
3,477 open-access articles · page 38 of 174
Research ArticleFactors Affecting the Absorption of Exosomes by Sertoli Cells
Ma Hong, Fu Bo, Wang Liang, Wang Fang, Guo Zhenhua, Liu Di
Exosomes play an important role in the signal transmission process of Sertoli (ST) cells. However, what factors affect the ability of ST cells to take up exosomes remains unclear. To investigate the influences of time, temperature, cytochalasin D (Cyt D), and…
10 Nov 2024DOI 10.17582/journal.pjz/20220727010714
Research ArticleEffect of Consistency of Diet on Swallowing and Blood Biochemical Components of Patients with Dysphagia After Brain Injury Surgery
Shuang Jin, Lishu Sun, He Wang, Yang Li
The objective of this study was to explore the effect of food consistency diet on different indicators and scales in patients with dysphagia after brain injury surgery. Patients (104) with traumatic brain injury who underwent surgical treatment were selected i…
10 Nov 2024DOI 10.17582/journal.pjz/20230315050318
Research ArticleEffect of Human Recombinant Activated Coagulation Factor VII (rFVIIa) on Total Bleeding Volume and Coagulation Function of Patients
Xiaolei Yan, Yabing Tang, Sainan Hu
The aim of this study was to analyze the effect of human recombinant activated coagulation factor VII (rFVIIa) on total bleeding volume and coagulation function of patients with postpartum hemorrhage (PPH). A total of 80 patients with PPH in Hunan Provincial M…
10 Nov 2024DOI 10.17582/journal.pjz/2023041107045- Research Article
The Value of Procalcitonin Combined with C-Reactive Protein Assay in the Early Clinical Diagnosis of Bloodstream Infection
Cheng-Hong Chen, Ling-Xian Ding
This study aims to investigate the application value of procalcitonin (PCT) paired with C-reactive protein (CRP) in the early diagnosis of bloodstream infection. This study involved 298 patients with suspected bloodstream infections who were hospitalized in ou…
10 Nov 2024DOI 10.17582/journal.pjz/20221011021005 - Research Article
Long Term Effects of SSRI Antidepressants on Levels of Different Serum Growth Factors in Patients with Depression
En Zhang, Ming Zhu, Wenli Zhu, Wei Xiong, Zhongfei Huang, Xin Qiao et al.
The objective of this study was to investigate the effect of long-term use of SSRI (selective serotonin reuptake inhibitors) antidepressants on serum nerve growth factor (NGF), glial cell line-derived neurotrophic factor (GDNF), vascular endothelial growth fac…
10 Nov 2024DOI 10.17582/journal.pjz/20230213200208 
Research ArticleEffect of Hypertension on Blood Lithium Level and its Concentration to Dose Ratio in Manic Episode Patients
Dan Liao, Mingchao Li, Zijun Xiong, Qiuming Ji, Ying Xia, Bing Liu et al.
The objective of this study was to further explore the influence of hypertension on blood lithium levels and its concentration to dose ratio (C/D) in patients with manic episodes. A total of 112 patients with manic episodes from the Wuhan Wudong Hospital betwe…
10 Nov 2024DOI 10.17582/journal.pjz/20230728161028
Research ArticleEnhanced Antitumor and Anti-Metastasis Efficiency via Combined Treatment with Carvacrol and Doxorubicin
Hu-Hu Chen, Xin Li, Mohd Hijaz Mohd Sani, Siat Yee Fong
Recent research on treatment of triple-negative breast cancer (TNBC) has focused on drug combinations that can improve their anticancer properties while minimizing adverse effects. This study investigated the efficacy of combined treatment with doxorubicin (Do…
10 Nov 2024DOI 10.17582/journal.pjz/20211208031233
Research ArticleEvaluation of Serum PAF, 1,25-(OH)2D3 and MMP-9 Levels in the Diagnosis of Kawasaki Disease and Prediction of the Risk of Coronary Artery Lesion
Wei Li, Hui Xu, Si Li, Jing Liu
The objective of this study was to investigate the serum platelet activating factor (PAF), 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) and matrix metalloproteinase-9 (MMP-9) levels in the diagnosis of Kawasaki disease (KD) and prediction of coronary artery lesion…
10 Nov 2024DOI 10.17582/journal.pjz/20221224081215
Research ArticleEffect of Remimazolam Combined with Propofol Anesthesia on Perioperative Cellular Immunity in Patients Undergoing Laparoscopic Ovarian Cyst Surgery
Xintao Dai, Zhenfeng Cai, Xingli Jiang, Pinglei Wu
The aim of this study is to investigate the effects of remimazolam and propofol anesthesia on perioperative immune cell levels in patients undergoing laparoscopic ovarian cyst surgery (LOCS). The sample of 90 LOCS patients was randomly divided to an experiment…
10 Nov 2024DOI Effect-of-Remimazolam-Combined-with-Propofol
Research ArticleGenetic Predisposition of PON1 L55M (T172A) and Oxidative Stress in Breast Carcinogenesis among Pakistani Population
Syeda Abiha Zehra Jaffari, Tuba Abid, Muhammad Zohaib, Ghulam Haider, Zehra Hashim
Breast cancer has become a global health issue across the world including Pakistan. In 2020, an estimated five-year prevalence of breast cancer is 30.1% depicting the major cause of socio-economic burden in our country. Owing to the fact that oxidative stress…
10 Nov 2024DOI 10.17582/journal.pjz/20221130081107
Research ArticleEfficacy of Amikacin Combined with Piperacillin/Tazobactam Sodium in Elderly with Severe Drug-Resistant Pseudomonas aeruginosa Pneumonia
Hongxiao Li, Xiying Wu, Dengxiang Wu, Jiangqing Yu
The purpose of this study was to demonstrate the effects of amikacin combined with piperacillin/tazobactam sodium (PPC/TS) in the therapy of severe resistant Pseudomonas aeruginosa (Pa) pneumonia in elderly individuals. The sample of 50 elderly patients with P…
10 Nov 2024DOI 10.17582/journal.pjz/20230524050529
Research ArticleAnalysis of Influencing Factors of Different COVID-19 Vaccinations on COVID-19 Infected Patients in Shanghai
Chonglin Yang, Cuiping Yang, Jingwen Jiang, Haifang Lai, Wenqiang Xia
Vaccination with COVID-19 vaccine can reduce the incidence of severe coronavirus infection and death. Different vaccinations have different impacts on patients who suffered COVID-19. However, the correlation between the dose and times of vaccination and the na…
10 Nov 2024DOI 10.17582/journal.pjz/20230304060316
Research ArticleRisk Factors Analysis of Hospital-Acquired Anemia in Cerebral Stroke Patients
Xinmin Liu, Fengming Ni, Lan Gao
We aimed to investigate the incidence and risk factors of hospital-acquired anemia (HAA) in stroke patients. We used retrospective analysis method, research on the incidence of HAA in 560 patients with cerebral apoplexy, the patients had incomed in the departm…
10 Nov 2024DOI 10.17582/journal.pjz/20220715060736- Research Article
Effect of Platelet-Rich Fibrin Combined with Guided Bone Regeneration on Bone Formation of Peri-Implant Bone Defects
Li Yang, Xuliang Ma, Chao Wang
Platelet-rich fibrin (PRF) combined with guided bone regeneration (GBR) is an emerging treatment method. The purpose of this study was to demonstrate the effects of PRF on the osteogenic ability of peri-implant bone defects. The sample of 67 patients who neede…
10 Nov 2024DOI 10.17582/journal.pjz/20230526070557 
Research ArticleAllele Frequency Distribution of CYP2C19*3 and CYP1A1 Allelic Variants Associated with Clopidogrel Resistance in Cardiac Patients of Pakistan
Kashif-ur-Rehman, Ahmad Bakhsh, Muhammad Akram Tariq, Muhammad Khalil Ahmad Khan, Sumaira Mehboob
Drug resistance is a phenomenon that has received serious attention nowadays in medical practice. Such is the case with clopidogrel treatment response, which is variable inter-individually and inter-ethnically due to genetic polymorphisms in Cytochrome P450 (C…
10 Nov 2024DOI 10.17582/journal.pjz/20230613100642
Short CommunicationAcute Toxicity of Four Disinfectants to Brine Shrimp, Artemia (Crustacea: Anostraca)
Song Jiang, Zhenhua Ma, Falin Zhou, Xu Chen, Jing Hu, Rui Yang et al.
In order to determine the impact of glutaraldehyde, dibromohydantoin, methionine iodine and bleaching powder on brine shrimp Artemia (crustacean, Anostraca), acute toxicity parameters were assessed. The analysis revealed a highest level of toxicity for bleachi…
8 Nov 2024DOI 10.17582/journal.pjz/20200623160651- Short Communication
Growth Performance of Labeo rohita Fingerlings Fed with Lactobacillus rhamnosus Supplemented Canola Meal and Corn Gluten-Based Feeds
Sadaf Aman, Yung Fu Chang, Javed Iqbal Qazi, Rahman Ullah, Farah Aman
The present study was carried out to record growth respose of Labeo rohita fingerlings fed with Lactobacillus rhamnosus supplemented feed. In a completely randomized design fishes were divided into two different treatments based on feeding with and without pro…
8 Nov 2024DOI 10.17582/journal.pjz/20220913080939 
Short CommunicationTGF-β Mediates the Role of P53 and microRNA-Related Signaling Pathways in the Pathogenesis of Diabetic Nephropathy in Rats
Yonghong Ma, Jinlan Ma, Qifu Zhang, Huajie Zou, Shenghua Ma
The objective of this study was to study the relationship between TGF-β-mediated P53 and microRNA-related signaling pathways and the occurrence and development of diabetic nephropathy. The sample of rats was randomly assigned to a control group and an exp…
8 Nov 2024DOI 10.17582/journal.pjz/20230316100317
Short CommunicationLatrine Site Selection by the Asian Badger (Meles leucurus) in a Temperate Forest of South Korea
Ho-Kyoung Bae, Jae-Kang Lee, Tae-Kyung Eom, Dong-Ho Lee, Hyeongyu Ko, Joo-Hee Kim et al.
This study was conducted to clarify the latrine site selection preference of the Asian badger Meles leucurus in a temperate forest, Pyeongchang, South Korea. Logistic regression models were used to determine which habitat variables affect latrine site selectio…
8 Nov 2024DOI 10.17582/journal.pjz/20230412120425
ReviewFreshwater Fish Biodiversity and Fisheries in Honghu Lake: Status, Threat and Conservation
Wen Xiong, Yifan Huang, Yue Liu, Shuyin Li, Baoqiang Wang
Honghu Lake is the seventh largest freshwater lake in China, and located in the centre of Yangtze River, which is the protection priority. Meanwhile, Honghu Lake is one of the most important regions of Chinese Fisheries. However, fish biodiversity and fisherie…
8 Nov 2024DOI 10.17582/journal.pjz/20231111073345