Table of Contents
Chapter 1: Introduction to Immune System
Time Line History of Immunology Branches of Immunology Immunity
Need for Self/Nonself recognition Pros and Cons of Immune system Summary
Need for Self/Nonself recognition Pros and Cons of Immune system Summary
References
Useful links
Useful links
Chapter 2: Structural Components of Immune System Hematopoiesis
Classification of blood cells
Lymphoid organs
Summary
References
Useful Links
Classification of blood cells
Lymphoid organs
Summary
References
Useful Links
Chapter 3: Antigens and Antibodies
Antigens
Antibody
Types of Immunoglobulins
Generation of monoclonal antibodies
Summary
References
Useful links
Antigens
Antibody
Types of Immunoglobulins
Generation of monoclonal antibodies
Summary
References
Useful links
Chapter 4: Immune Receptors
Immune Receptors
Pattern recognition receptors (PRRs)
Killer activation receptors (KARs)
Killer inhibition receptors (KIRs)
Fc receptors
Complement receptors (CRs)
B and T cell receptors
Summary
References
Useful links
Immune Receptors
Pattern recognition receptors (PRRs)
Killer activation receptors (KARs)
Killer inhibition receptors (KIRs)
Fc receptors
Complement receptors (CRs)
B and T cell receptors
Summary
References
Useful links
Chapter 5: Cytokines and Cytokine Receptor Mediated Signalling Cytokines
Classification of cytokines
Cytokine Antagonism
Cytokines and Diseases
Cytokine Based Therapies
Summary
References
Useful links
Classification of cytokines
Cytokine Antagonism
Cytokines and Diseases
Cytokine Based Therapies
Summary
References
Useful links
Chapter 6: Innate Immune Responses
First Line of defense
Second line of defense
First Line of defense
Second line of defense
Summary
References
Useful links
Chapter 7: Antigen Presentation and Processing
Discovery of MHC molecule
General Structure of MHC Molecules
The antigen Processing Pathways
Cross Presentation of Antigens
Presentation of Non-peptide Antigens
Summary
References
Useful links
Chapter 8: Development of B Lymphocytes
Hematopoiesis during gestation
Developmental stages of B lymphocytes
Development of B1 and marginal B cells
Pathological conditions related to B cells
Summary
References
Useful links
Chapter 9: Activation and Effector Functioning of B Lymphocytes
T Dependent Responses
T Independent Reponses (TIR)
Effector functions mediated by antibodies
Features of Ig isotypes
Negative regulation of B cells
Summary
References
Useful links
Chapter 10: Development of T Lymphocytes
Thymocyte development inside thymus
Development of Thymocyte Receptors
Thymic Selection of Thymocytes
DP Thymocyte commitment to single positive (CD4 or CD8) T cells
Final maturation of thymocytes
Development of self-tolerance due to T cells
Summary
References
Useful links
Chapter 11: T Cell Activation and Effector Functions
Activation of T lymphocytes
Differentiation of T cells
TH1/TH2 and TH17/TREG Paradigm
T cell recognition of Antigens and their effector functions
Summary
References
Useful links
Chapter 12: Tumor Immunology
Malignant transformation
Genetic basis for tumor development
Host immune response to cancer
Mechanisms promoting the tumor growth
Cancer therapies
Evasion of tumor cells from the host immune system
Summary
References
Useful links
Chapter 13: Immune Disorders
Primary immune disorders
Secondary Immune Disorders
Hypersensitivity Reactions
Autoimmune disorders
Summary
References
Useful links
Chapter 14: Vaccine Immunology
History of vaccination
Vaccination Vs Immunization
Types of vaccines
Adjuvants & Preservatives in Vaccines
Vaccine Delivery Systems
Vaccine administration Routes
Efficacy of Vaccines
Vaccine Failure
Reverse Vaccinology
Vaccination Strategies
Safety of using Vaccines
Summary
References
Useful links
Chapter 15: Diagnostic Immunology
Immunoprecipitation Reactions
Agglutination Reactions
Complement Fixation Test (CFT)
Neutralization Reactions
Radioimmunoassay (RIA)
Enzyme Linked Immunosorbent Assay (ELISA)
Enzyme linked immunospot assay (ELISPOT assay)
Fluorescent Antibody Technique
Flow Cytometry
Immunohistochemistry
Western Blotting
Future Prospects
Summary
References
Useful links
List of Abbreviation
