Immunohistochemical Estimation of Apoptotic Activity and Testosterone Level in the Testes of Rats after Chronic Exposure to Uranium Acetate
Immunohistochemical Estimation of Apoptotic Activity and Testosterone Level in the Testes of Rats after Chronic Exposure to Uranium Acetate
Heba Saleh Shaheed*, Muna Abdul Sahib Alkhfaji, Ghusoon Abdul Kareem Neamah
Histopathological section of rat testis; A: for GI group showing normal histological structures, B: for GII group showing severe thickening in blood vessels wall and congestion in their lumen (black arrow). Also vacuolation in the germinal cells (red arrow) (H and E, stains, 200x).
Histopathological section of rat testis for GII group; A: showing interstitial thickening with hyalinization (black arrow) (H and E, stains, 200x); B: severe necrosis (nuclear changes) in the germinal cells (head arrow) and apoptosis also seen (red arrow) (H and E, stains, 400x).
Immunohistochamical section of rat testes; A: for GI group; B: for GII group showing positive rection for apoptotic activity appear as dark brown color of spermatogonia (DAB chromogen stain, 200x).
levels (mean±SE) of testosterone in serum (nmol/ml) of rats treated with Uranyl acetate for 90 day.
