Promy Virk
...ract and to evaluate the anti-diabetic activity of the prepared nanopcomposite. Antidiabetic potential of orally administered bulk aqueous extract of Trigonella (TBE) and Au/Ag nanocomposite with Trigonella seed extract (TN) on streptozotocin (70 mg/kg) induced diabetic rats was assessed for a period of 7 weeks. Metformin was used as a standard drug. The results of Zetasizer and Transmission and Scanning Electron Microscopy images showed the pres...
Atiq-ur-Rehman1,2,*, Abida Latif1,*, Rukhsana Anwar1, Nasir Abbas1, Sajid Nawaz2 and Hamid Turab Mirza3
...itro, in vivo anti-diabetic potential and mode of action of various fractions of methanolic extract of the aerial parts of this plant. Various fractions (n-hexane, chloroform, ethyl acetate and n-butanol) from the most active methanolic extract were prepared. Hypoglycemic potential was investigated by α-amylase inhibitory assay. Different concentrations of fractions (20-100 µg/ml) were subjected to in vitro α-amylase inhibit...
Tanveer Ahmad1, Tariq Mehmood1, Muhammad Shahid1, Adnan Ahmad1,2, Muhammad Asim Raza Basra1, Muhammad Zia-ur-Rehman3* and Munawar Ali Munawar1
Sumaira, Ali Mujtaba Shah*, Ghulam Asghar Solangi, Ifra Anwar, Qudratullah Kalwar
...ntiviral, antibacterial, anti-diabetic, anti-carcinogenic and anti-ageing. Besides, camel milk contains abundant proteins which are conductive to improve the immunity functions. Thus, it is necessary to illuminate the beneficial impact of camel milk and its composition.
A.M. Abdul Azeem, Ashraf M. Mounir and Amr N. El-Shahat*
Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3
...g leaves have comparable anti-diabetic efficacy to that of a glibenclamide administration. This suggests a promising prospect in developing novel drugs for treating diabetes mellitus.
Keywords | Anti-diabetic, Cola acuminata, Antioxidant, Alloxan, Glibenclamide, Wistar rats, Experimental work
... 
Waheed Khan1, Muhammad Ajmal Khan2, Bakhtawar Khan1*, Aftab Amin3, Muhsin Ali4, Awais Farid, Ali Hazrat5 and Muhammad Yahya5
...f V. thapsus have potent anti-diabetic activity, with comparatively less toxicity for its use in ethno-medicine for diabetes management....
Aamir Ali, Hafiz Muhammad Tahir*, Azizullah, Shaukat Ali, Muhammad Farooq Bhatti, Muhammad Summer and Ali Haidar Gormani
...tibacterial, anticancer, anti-diabetic and antidepressant activities. Further studies should explore the mulberry leaves potentials as these plants have got the attention of both the pharmacological and commercial industries.
Novelty Statement | The mulberry leaves possess various therapeutic potentials. In this study, we have summarized all the therapeutic potentials of different mulberry leaves extr...
ASIFA BASHIR1, AAMIR MUSHTAQ2* & TOOBA MEHBOOB3
...hyllanthus emblica as an anti-diabetic agent in hyperglycemic patients. Ethanolic extract of its dried fruits was analyzed both qualitatively and quantitatively for evaluation of phytochemical agents. Then its antioxidant and anti-diabetic activities were found. The results indicated the presence of carbohydrates, tannins, phenols, alkaloids, flavonoids, saponins, glycosides, amino acids and proteins in crude extract with ph...
Iram Alam Sthanadar1*, Muhammad Zahid1, Sami Siraj2 and Omar Malik2
...Us) are widely used oral anti-diabetic drugs metabolized by cytochrome P450 belonging to family 2 subfamily C member 9 (CYP2C9). CYP2C9 has shown better glycemic control and reduced the treatment failure rates compared to metformin and its combination therapy. To study the association of CY2PC9 gene variant rs1057910 in T2DM patients of Khyber Pakhtunkhwa (KP) origin, the cohort study was conducted for a period of 12 months including 150 patients receiving met...
Sana Eijaz, Asmat Salim* and Mohammad Anwar Waqar
... sinensis are well known anti-diabetic nutritional herbs. However, inadequate data is available regarding their molecular mechanism of action. In this study, we used a new combination of the aforementioned herbs and Trigonella foenum graceum as a separate treatment. We investigated their effect on the blood glucose level, body weight, expression of some of the insulin signaling genes in skeletal muscle and adipose tissue including insulin receptor (INSR), insu...
Mohamed H.M. Abd El-Megid1, A.N. El shahat2, A.M. Abdul Azeem2* and Amal A. Mansour2
Wafa H. Alamshani*; Faisal Al-Sarraj; Mashail A. Algamdi
...ammatory, antimicrobial, anti-diabetic, antiatherosclerotic,
and many other biological effects. Consequently, the purpose of this review
was to highlight the inhibitory potential of P. granatum extracts on E. coli and K. pneumonia
pathogens, to be used in the effective management of UTIs.
... 
