Search for Anti-diabetic

Antidiabetic Activity of Green Gold-Silver Nanocomposite with Trigonella foenum graecum L. Seeds Extract on Streptozotocin-Induced Diabetic Rats

Promy Virk

...ract and to evaluate the anti-diabetic activity of the prepared nanopcomposite. Antidiabetic potential of orally administered bulk aqueous extract of Trigonella (TBE) and Au/Ag nanocomposite with Trigonella seed extract (TN) on streptozotocin (70 mg/kg) induced diabetic rats was assessed for a period of 7 weeks. Metformin was used as a standard drug. The results of Zetasizer and Transmission and Scanning Electron Microscopy images showed the pres...

Postprandial Anti-Diabetic Effects of Various Fractions of Fagonia indica Burm. f. by in vitro and in vivo Studies

Atiq-ur-Rehman^1,2,*, Abida Latif^1,*, Rukhsana Anwar¹, Nasir Abbas¹, Sajid Nawaz² and Hamid Turab Mirza³

...itro, in vivo anti-diabetic potential and mode of action of various fractions of methanolic extract of the aerial parts of this plant. Various fractions (n-hexane, chloroform, ethyl acetate and n-butanol) from the most active methanolic extract were prepared. Hypoglycemic potential was investigated by α-amylase inhibitory assay. Different concentrations of fractions (20-100 µg/ml) were subjected to in vitro α-amylase inhibit...

In vivo Anti-Diabetic Studies of Sulfonylurea-Sulfonamide Hybrids

Tanveer Ahmad¹, Tariq Mehmood¹, Muhammad Shahid¹, Adnan Ahmad^1,2, Muhammad Asim Raza Basra¹, Muhammad Zia-ur-Rehman³* and Munawar Ali Munawar¹

Composition and Beneficial Impact of Camel Milk on Human Health

Sumaira, Ali Mujtaba Shah*, Ghulam Asghar Solangi, Ifra Anwar, Qudratullah Kalwar

...ntiviral, antibacterial, anti-diabetic, anti-carcinogenic and anti-ageing. Besides, camel milk contains abundant proteins which are conductive to improve the immunity functions. Thus, it is necessary to illuminate the beneficial impact of camel milk and its composition.

Studying the Anti-Diabetic Effect of Gamma-Irradiated Pumpkin Seeds

A.M. Abdul Azeem, Ashraf M. Mounir and Amr N. El-Shahat*

Antidiabetic and Antioxidative Potentials of Aqueous Extract of Cola Acuminata Leaves in Alloxan-Induced Diabetes Mellitus in Male Albino Rats

Owolabi Olutunmise Victoria¹*, Saka Olusola Stephen², Olashinde Oluwaseun Ruth¹, Alli Smith Yemisi Rufina³

...g leaves have comparable anti-diabetic efficacy to that of a glibenclamide administration. This suggests a promising prospect in developing novel drugs for treating diabetes mellitus.

Keywords | Anti-diabetic, Cola acuminata, Antioxidant, Alloxan, Glibenclamide, Wistar rats, Experimental work

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Evaluation of Antidiabetic and Antihyperlipidemic Effects of Methanolic Extract of Verbascum thapsus in Alloxan-Induced Diabetic Albino Mice

Waheed Khan¹, Muhammad Ajmal Khan², Bakhtawar Khan¹*, Aftab Amin³, Muhsin Ali⁴, Awais Farid, Ali Hazrat⁵ and Muhammad Yahya⁵

...f V. thapsus have potent anti-diabetic activity, with comparatively less toxicity for its use in ethno-medicine for diabetes management.

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Applications of Mulberry Leaves: An Overview

Aamir Ali, Hafiz Muhammad Tahir*, Azizullah, Shaukat Ali, Muhammad Farooq Bhatti, Muhammad Summer and Ali Haidar Gormani

...tibacterial, anticancer, anti-diabetic and antidepressant activities. Further studies should explore the mulberry leaves potentials as these plants have got the attention of both the pharmacological and commercial industries.

Novelty Statement | The mulberry leaves possess various therapeutic potentials. In this study, we have summarized all the therapeutic potentials of different mulberry leaves extr...

Evaluation of Antioxidant and Antidiabetic Activity of Phyllanthus emblica (Fruit)

ASIFA BASHIR¹, AAMIR MUSHTAQ²* & TOOBA MEHBOOB³

...hyllanthus emblica as an anti-diabetic agent in hyperglycemic patients. Ethanolic extract of its dried fruits was analyzed both qualitatively and quantitatively for evaluation of phytochemical agents. Then its antioxidant and anti-diabetic activities were found. The results indicated the presence of carbohydrates, tannins, phenols, alkaloids, flavonoids, saponins, glycosides, amino acids and proteins in crude extract with ph...

A Cohort Study on Response of T2DM Patients to Oral Antidiabetics and their Association with CYP2C9*3 Gene Polymorphism (rs1057910) in Khyber Pakhtunkhwa, Pakistan

Iram Alam Sthanadar¹*, Muhammad Zahid¹, Sami Siraj² and Omar Malik²

...Us) are widely used oral anti-diabetic drugs metabolized by cytochrome P450 belonging to family 2 subfamily C member 9 (CYP2C9). CYP2C9 has shown better glycemic control and reduced the treatment failure rates compared to metformin and its combination therapy. To study the association of CY2PC9 gene variant rs1057910 in T2DM patients of Khyber Pakhtunkhwa (KP) origin, the cohort study was conducted for a period of 12 months including 150 patients receiving met...

A New Herbal Combination and Trigonella foenum graceum Improve Insulin Resistance, Insulin Signaling Genes, Adipokines Level and Body Weight in Type 2 Diabetic Rat Model

Sana Eijaz, Asmat Salim* and Mohammad Anwar Waqar

... sinensis are well known anti-diabetic nutritional herbs. However, inadequate data is available regarding their molecular mechanism of action. In this study, we used a new combination of the aforementioned herbs and Trigonella foenum graceum as a separate treatment. We investigated their effect on the blood glucose level, body weight, expression of some of the insulin signaling genes in skeletal muscle and adipose tissue including insulin receptor (INSR), insu...