Atul Sharma, Aruna Chandra Singh, Gautam Bacher, Sunil Bhand
...sed as bacteriostatic or bactericidal agents either to kill or inhibit the growth of microorganisms. Their abuse results in various side effects on the human health, environment and agriculture. The occurrence of bacterial “suprainfection” with tolerance to antibiotics has attracted the significant attention, mainly due to the consequences of multi drug resistance and potential threat to human health and the environment. With the increasing inciden...
Iram Liaqat1*, Najma Arshad2, Muhammad Arshad3, Safdar Ali Mirza4, Nazish Mazhar Ali1 and Ammara Shoukat1
...ration (MIC) and minimum bactericidal concentration (MBC) of plant extracts was also determined. Syzygium aromaticum was proven to have excellent antimicrobial activity against all tested microorganisms, while C. sinensis and M. piperita showed weak antimicrobial activity. Methanolic plant extracts exhibited greater antimicrobial activity than aqueous extracts. Maximum zone of inhibition exhibited by methanolic extracts of S. aromaticum was 10 mm and 20 mm in ...
Hao Gu*, Zhi Yang, Weiqiang Yu, Kan Xu and Yuan-fei Fu*
...evaluated by the minimal bactericidal concentration, change of pH in the first 12 h and OD values of biofilms. Besides, fluorescent images of exopolysaccharides and living bacteria of Streptococcus mutans were measured with confocal laser scanning microscopy (CLSM). In our study, capsaicin showed an outstanding performance in the inhibition of acid producing and biofilm of the four strains of cariogenic bacteria. Meanwhile, low values of MIC of capsaici...
Shahida Sabir1, Anwar Ali Shad1, Tariq Masood1*, Zafar Ali Shah1, Nasiruddin2, Yaseen Ahmad1 and Syed Sartaj Alam3
...of mushroom proved to be bactericidal with highest % inhibition (65, 36 and 75 %) recorded at 25 mg/L concentration against all the three bacterial strains i.e., E. coli, Staphylococcus aureus and Xanthomonas sp., respectively. Maximum % inhibition (about 50%) was recorded at 25 mg/L concentration against all the three fungal species (Penicillium claviforme, Aspergillus flavus and Fusarium sp.). Methanolic extract of P. eryngii showed increasing % mortality ag...
Xiaoli Cai1,2, Saeed Ahmed3, Zhixin Lei1,*, Jianping Wu1,* and Taolei Sun1,2,*
...chanism of bacteria, the bactericidal mechanism of antibiotics, the way of nanoparticles overpasses the cell membrane and approaching the cell, the strategies, prospects and challenges of nanoparticles treating intracellular bacteria.
...
Jiang Wu*
... (MIC) value and minimum bactericidal concentration (MBC) value were measured. The virulence gene expression of the four foodborne pathogens was analyzed by quantitative real-time PCR (qRT-PCR). A microplate reader was used to monitor cell growth at 600 nm with 1 h interval. Environmental scanning electron microscope (ESEM) was used to analyze morphological changes of E. coli and Staph. aureus cells. ATP analysis kit and EnSpire microplate reader were used to ...
Faiza Ghazanfar1, Masood Rabbani1*, Aamir Ghafoor2 and Muhammad Hassan Mushtaq3
... study was to define the bactericidal action of organic acids on Campylobacter jejuni, individually and in combination. Total 120 broiler chickens were randomly distributed in ten groups. The groups included negative and positive control, pure organic acid group and commercial organic acid formulation group. Excluding negative control group, all other groups were orally challenged with 0.1 ml of the 6-Log 10 CFU/ml of the Campylobacter jejuni culture in normal...
Hassan A. Aidaros, Eman M. Hafez, Halla E.K. El Bahgy*
... organic matter hindered bactericidal power of many commercial disinfectants such as quaternary ammonium compounds (QUATS), halogen releasing agents including iodine, chlorine and its compounds, but some were not affected, such as glutaraldehyde. Finally, the success of the disinfection process in different poultry farms mainly depends on the selection of suitable disinfectants.
Keywords | Disinfectant, Poultry, E.coli, Pasteurella multocida, Campyloba...
Mai A Fadel1*, Ahmed M Elmahdy1, Jihan Mostafa Badr2, Mohammed AM Saleh3, Mona A.A. AbdelRahman3
...y concentration, minimum bactericidal concentration, and fractional inhibitory concentration were determined. High Performance Liquid chromatography (HPLC) method was developed to quantify the concentrations of enrofloxacin and amoxicillin in serum and different tissues of chickens. The pharmacokinetics and pharmacodynamics indices of both antibiotics were calculated and statistically analyzed. Aspartate aminotransferase, alanine aminotransferase, urea, and cr...
A. Yu. Aliev1*, A.A., Aliev1, A.M. Musaev1, M.Z. Magomedov2
Khasan Khamidovich Shakhbiev1*, Saidkhamzat Saidmagomedovich Abumuslimov1, Larisa. Vakhaevna Taramova1, Islam Khasanovich Shakhbiev1, Svetlana Aleksandrovna Shemyakova2
...effectiveness of the new bactericidal-anthelmintic composition azitroprazifen at a dose of 20 mg / kg body weight with ground beef of in echinococcosis young of dogs complicated by streptococcosis was high in our experience. In all 100% of the experimental dogs, on the 7th day after treatment, there was a complete absence in feces of eggs of E. granulosus and bacteria of the genus Streptococcus and an improvement in the physiological state of the body. In the ...
Tabark F Ahmed, Nibras Z. Yahya*
... highest synergistic and bactericidal effect. It was determined that in vitro study against E. coli O157 in the treatment of urinary tract infection, the combination of ascorbic acid and ciprofloxacin was both more potent and safer than the combination of ascorbic acid and erythromycin. From this study concluded the combination of ciprofloxacin, and erythromycin against isolated E. coli showed that this microorganism is highly sensitive to ciprofloxacin and re...
Iram Liaqat1*, Noor Muhammad1, Muhammad Mubin2, Najma Arshad3, Tehreema Iftikhar4, Sumera Sajjad5 and Farzana Rashid5
...ration (MIC) and minimum bactericidal concentration (MBC) of screened Actinomycetes was in the range of 1.3 - 3.5 mgmL-1 and 1.9 – 4.0 mgmL-1 of bacterial biomass, respectively. Three isolates, S. monticola, S. septentrionalis and S. polaris showed 100 % mortality at 1000 ppm against Anopheles 3rd instar larvae. These findings indicated that actinobacterial isolates possess antibacterial and larvicidal potential. Further extraction and purification of bi...
Orooba Mohammed Saeed Ibrahim1*, Rawaa Saladdin Jumaa2, Nibras Zeyad Yahya1
...ously bacteriostatic and bactericidal against the examined bacteria depending on concentration. Phytochemicals analysis indicated the presence of alkaloids, phenol, saponins, flavonoids, tannins, and glycosides. The test organism was more sensitive to C. limonum compared to C. aurantium. The MICs ranged from 1.56 to 12.5mg/ml; MBCs, (3.125 - 25mg/ml) and MBC/MIC ratios (2.0-4.0). Furthermore, a time killing curve of each 4x MICs and 8x MICs concentrations of j...
Ahmed M. Manthoor, Ali H. Saliem*
...on (MIC) and the minimum bactericidal concentration (MBC), by using 4, 8, 16, 32, 64 and 128 mg/ml concentration of the extract, while 1.562, 3.125, 6.25, 12.5, 25, 50, 100, 200, 400, 800 µg/ml concentration of Ciprofloxacin, on the other hand study mechanism of action of the extract against the same bacteria by Fe-Scanning Electron Microscopic(Fe-SEM). The extraction ratio was (15%) and the phytochemical analysis referred to the presence of alkaloids, f...
UZMA BASHIR,Amna Ali,MUHAMMAD SALEEM HAIDER,Naureen Akhtar
H.A. Abdul-Ratha1*, Sahar Mahdi Hayyawi2, Essam F. AL-Jumaily3
... formation important for bactericidal activity against cell membrane with highly potent for the treatment against Staphylococcus aureus infection. In addition, the treatment with combination between acidocin and biofilm lead to lysis of cytoplasm, nucleic acid destruction, disappearance and vacuolization in Staphylococcus aureus cells. The treatment with combination between acidocin and biofilm lead to lysis of cytoplasm, nucleic acid destruction, disappearanc...
Aamir Sohail1, Irshad Ali Khan2*, Ahmed Shamkhi Jabbar3, Mehran Gul2, Sidra Ahmad4, Nayab Ahmad4, Farzana6, Abdur Rehman5, Arooba Bashir4, Syed Muhammad Owais Shah2 and Ayesha Alam7
...-volatile compounds with bactericidal properties. Consequently, this process effectively suppressed pathogen populations in the soil, contributing to the control of bacterial wilt. Based on these findings, adding 42 g of dried N. oleander powder per kilogram of soil has the potential to effectively suppress bacterial wilt in tomatoes and potentially other vegetables. These findings suggest that dried Nerium oleander powder, particularly at a dosage of 42 g/kg ...
Dadile M. Abdulrahman 1 Abdullahi M. Daskum 1 Kura M. Abdulrahim 1 Abubakar M. Dadile 2 Hajja Amma 3
Volume 1, Issue 1, November and December 2017, Pages 3-13
...ration (MIC) and Minimum bactericidal concentration (MBC) of the AGE against the bacterial isolates at 37oC. Investigating the activity of AGE loaded on Gel dressing revealed that it can have potency when applied on patients with Staphylococcal skin infections. Findings from this study encourage and support the use of AGE in treating bacterial skin infections especially in developing countries like Africa, as it is available, economic and have no side effects....
Solange Gahongayire 1 Ibrahim Ntulume 1 Kagimbura Ervine 2 Bizimana Évariste 2 Adamu A. Aliero 3
Volume 2, Issue 6 November and December 2018 Pages 156-166
...ations (MIC) and Minimum bactericidal concentrations (MBC) were also determined. Results showed that crude extracts of leaves and fruits of C. annum had antibacterial efficacy against
Waithaka, P.N.1*; Mwaura, F.B.1; Wagacha, J.M.1; Gathuru, E.M.2; Githaiga, B.M.2
Novel Research in Microbiology Journal (2019), 3(3): 351-365
...entration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentration (MFC) of the antimicrobial metabolites extracted from PAN 30, PAN 37, PAN 41 and PAN 154 isolates were equal. The Half Lethal Concentration (LC50) in (μg/ ml) for the antimicrobial metabolites extracted from the 4 isolates were; PAN 30 (1.8168 ± 0.47), PAN 37 (3.4269 ± 0.56), PAN 41 (3.4269 ± 0.45), and PAN 154 (4.9397 ± 0.41). The fou...
Zakaria Ahmed1
Novel Research in Microbiology Journal (2019), 3(6): 485-492
...hat TTO exerts a greater bactericidal potency against biofilm-grown methicillin-resistant Staphylococcus aureus (MRSA), and methicillin-sensitive Staph. aureus (MSSA) strains. Moreover, tea has inhibitory efficacy against the carcinogenic bacteria....
Andriantsihoarana J. Razanatseheno1; Lovarintsoa J. Randriamampianina1; Hanitra R. Randrianarivo1; Danielle A. D. Rakoto1; Victor L. Jeannoda1*
Novel Research in Microbiology Journal (2019), 3(6): 502-510
...f the extracts expressed bactericidal potency against the tested bacterial spp. Current results revealed the antibacterial potential of the Albizia mahalao leaves and root bark extracts thus could be used to treat infectious diseases....
Nouran H. Assar1*; Aya allah T. Mohamed2,3; Rehab M. Abd El-Baky2,3; Reham Ali Ibrahem2
Novel Research in Microbiology Journal (2021), 5(3): 1256-1268
...ile the recorded minimum bactericidal concentration (MBC) was 284 μg/ ml. The mode of action of the AgNPs was investigated using the Scanning electron microscope (SEM), which was recognized as bacterial cell lysis and elongation. Current data suggest an efficient biosynthesis of stable AgNPs by B. subtilis with remarkable antibacterial potential. ...
Basma T. Abd-Elhalim*
Novel Research in Microbiology Journal (2022), 6(6): 1783-1800
...s ATCC 7080. The minimum bactericidal concentration (MBC) of the M. oleifera leaf powder was equivalent to 25.0 μg\ ml for Enterococcus faecalis, 12.50 μg\ ml for S. typhi, and 6.25 μg/ ml for E. coli and Shigella sonnei. Biocompatibility of the M. oleifera leaf powder was confirmed using the oral epithelial cell lines (OEC), which recorded an IC50 of 716.1 μg\ ml, whereas cell viability of 100.0, 94.1, 90.5, and 88.0 % was observed on application ...
Zine El Abidine Bzazou El Ouazzani1; Laila Reklaoui1; Houda Benaicha1,2; Said Barrijal1*
Novel Research in Microbiology Journal (2024), 8(4): 2491-2509
...ring the mcr-1 gene. The bactericidal activity of the CS@OM combination was achieved through various mechanisms, including bacterial membrane disruption and leakage of internal bacterial constituents, leading to bacterial death. Consequently, the CS@OM combination evinced a high capacity to prevent the development of drug resistance in the examined isolates. To the best of our knowledge, this is the first study to appraise the combination of colistin and Origa...
Aulia Kanwal1, Rehana Kausar2, Muhammad Asif Gondal1* and Chi Chen3
...t microflora, skin mucus bactericidal activity, blood serum lysozyme, and bactericidal activity against Shigella sonnei, and hematological parameters were evaluated. Significant difference in growth performance of red tilapia fed with experimental diets was observed. RGR (relative growth rate) was lowest in BD (380.79 ± 46.26) and observed highest in RH (554.01 ± 83.24). Lactobacillus count was increased in all...
Lakhdar Benalach1*, Fadhela Boukada2, Kouider Cherifi1, Ali Latreche1, Ikram Messellem3 and Mohammed Bellatreche4
...e, MIC, and MBC (minimal bactericidal concentration) of 30 mm, 4.68 mg/ ml, and 9.36 mg/ ml, respectively. The extracts from Ononis spinosa showed a high antibacterial efficacy, thus they may have potential applications in food and pharmaceutical products....
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Investigating the Bioactive Potential of Ononis spinosa L. Phytochemical Profiling and Antibacterial Effectiveness Evaluation
Lakhdar Benalach, Fadhela Boukada, Kouider Cherifi, Ali Latreche, Ikram Messellem and Mohammed Bellatreche
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Bioactivity of the Endophytic Bacteria Inhabiting the Egyptian Medicinal Plant Hyoscyamus muticus
Noura Sh. A. Hagaggi, Marwa E.A. Khalaf and Eman A. El Rady
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