Shakeel Ahmed* and Sarwat Jahan
...adipokines (adiponectin, leptin and resistin) secretion in 48-h fasting and normal fed adult male Rhesus monkeys. After NMS administration plasma adipokines levels were determined in fed and fasting monkeys. Four intact adult male monkeys were used in this study. 50 nmol of NMS was injected intravenously. Blood samples were collected individually 60 min before and 120 min after NMS administration at 15 min intervals. The plasma adipokines concentrations were d...
Wan-Long Zhu1 and Guang Yang2,*
...mass, food intake, serum leptin levels and hypothalamic neuropeptide neuropeptide Y (NPY), Agouti related peptide (AgRP), pro-opiomelanocortin (POMC), cocaine and amphetamine regulated transcript (CART) expressions were measured. The results showed that short photoperiod reduced body mass and body fat mass, and increased food intake. But serum leptin levels showed no significant differences between short photoperiod group an...
Physiological Responses to Fasting and Refeeding in Apodemus chevrieri from Hengduan Mountain Region
Hai-Ji Zhang1, Di Zhang2, Dong-Min Hou1 and Wan-Long Zhu1,*
...organs morphology, serum leptin levels and food intake were measured in the present study. The results showed that food deprivation decreased body mass and body fat mass. After refeeding, body mass can not be returned to the control value on refeeding 12 h, and it returned to control level on refeeding 7 days, but body fat mass can not be restored to the control level on refeeding 7 days. RMR and mass of liver decreased significantly in fasting groups, which c...
Wenqiao Hui1, Jishun Tang1, Dejian Zhu1, Qian Ban2* and Sheng Chen1*
...It has been demonstrated leptin act as a critical metabolic cue linking adipose and the onset of puberty. In the present study, we first assessed the morphological changes in adipose tissue at pre-puberty and puberty onset stages of goats, and then determined the role of leptin to activate signaling pathways which modulate the expression of hypothalamic genes involved in reproduction and metabolism. We found that
Shabana1,*, Farah Ehsan1 and Shahida Hasnain1,2
... triglycerides, HDLC and leptin. In conclusion, Gly482Ser variant appears to be significantly associated with diabetes in Pakistani population. The variant appeared to exert its effect by changing serum fasting plasma glucose, total cholesterol and LDLC levels.
...
Selçuk Kaplan1,* and Sertaç Atalay2
...ctor 1 (IGF1) and leptin (LEP) genes in Kivircik crossbred ewes. Therefore, IGF1/BfoI and Lep/BcnI polymorphisms were examined by polymerase chain reaction- restriction fragment length polymorphism method. The single nucleotide polymorphism (SNP) in the regulatory region of the IGF1 gene was detected by amplification of the 294 bp region using specific primers and cleavage with the BfoI enzyme. Allele frequencies of A ...
Ali Haider Saleem1,*, Khalid Javed2, Masroor Ellahi Babar3, Tanveer Hussain3, Asad Ali2, Afzal Ali2, Nisar Ahmad2, Muhammad Zahid Farooq1 and Muhammad Dawood2
Lili Zhang, Yuanxiao Wang, Yili Kong, Hussain Ahmad, Rui Yan, Li Dong, Jingfei Zhang and Tian Wang*
...6 days of age. The serum leptin level was significantly higher (P<0.05) in the IUGR pigs at 28 days of age while it decreased significantly (P<0.05) at 160 days of age as compared to the NBW pigs at the same age. Fatty acid composition of the longissimus dorsi muscle was not affected by IUGR (P>0.05). Furthermore, b*, L*, and C* values, pressure loss, and the ratio of MyHC IIb to other isoforms of the longissimus dorsi musc...
Selçuk Kaplan
...ies. Therefore, bubaline leptin gene exon 2, part of the intron 1 and intron 2 region were amplified and sequenced to identify nucleotide variations in Anatolian water buffaloes. Sequence analysis were revealed seven polymorphic site (G1072A, T1081C, T1131G, T1143C, T1145G, T1151G and C1221T) and one monomorphic site (C1071T) in Anatolian water buffaloes. To the best of my knowledge, this is the first study that fully describes seven polymorphic sites of bubal...
Yue Ren1, Peng-Fei Liu2, Wan-Long Zhu1,*,Hao Zhang1 and Jin-Hong Cai1
...NST), food intake, serum leptin levels and hypothalamic neuropeptide Y (NPY), agouti aelated peptide (AgRP), pro-opiomelanocortin (POMC), cocaine and amphetamine regulated transcript (CART) expressions were measured. The results showed that body mass and serum leptin levels were lower significantly in winter than that of in summer in five areas. But thermogenic characteristics and food intake were higher significantly in win...
Elmas Ulutaş1,*, Abdullah Eryavuz2, Aziz Bülbül2, Abdur Rahman3,*, İsmail Küçükkurt4 and Cangir Uyarlar5
...ut decreased (p<0.05) leptin and malondialdehyde concentration while other parameters remained unaffected. No difference was observed in ruminal pH between the treatment groups. Ruminal ammonia and number of protozoa were decreased (p<0.05) with 700 ppm and 1000 ppm zinc supplementation. Rumen Zn concentration increased (p<0.05) in the goats fed with 1000 ppm zinc, whereas there was no difference in rumen Fe and Cu concentration among the treatments, ...
HuaBin Zhang1,2, YaSen Li1, Tao Pan1, Peng Yan1, En Li1, Hui Xue1 and XiaoBing Wu1,*
...dicated that the role of leptin is much broader, such as the regulation of reproduction and hibernation. But so far the limited study of leptin and its receptor has investigated in Chinese alligator, Alligator sinensis. Therefore, we reported the presence and location of leptin and its receptor in different tissues of Chinese alligator by immunohistochemistry analysis. This study ai...
Gong Xue-na1, Jia Ting2, Zhang Di2 and Zhu Wanlong1*
...activity behavior, serum leptin levels, hypothalamic neuropeptide expressions and body compositions were measured. The results showed that regions and HF diet affected body mass, food intake and RMR significantly, HF diet increased body mass in E. miletus, while regions had significant effect on activity behavior, but HF diet had not affect activity behavior. Regions and HF diet also showed remarkable effects on leptin
Ahmed M. Darwish1*, Hassan R. Darwish1, Dalia M. Mabrouk1, Mohamed A. Abdelhafez1, Ahmed M. Abdel-Salam2, Ibrahim E. Mohamed3, Ibrahim M. Farag1
Emtenan M. Hanafi1*, Fouad M. Tawfeek2, Walid S. El Nattat1, Moetazza M. Alshafei3, Seham S. Kassem3, Kawkab A. Ahmed4, Enas N. Danial5, Hagar Elbakry3, Hoda S. El-Sayed2
... elevated lipid profile, leptin, oxidative markers and low level of testosterone and the epididymal Spermatozoa had low sperm viability and higher abnormalities than control group. Feeding the microcapsules (G2,G3) improved the animals’ health condition. Animals in G2 showed good spermatozoa profile while, those fed SP (G3) showed low sperm count and motility. Histopathological examination declared testicular degeneration in G1 and G3 and a high spermato...
Hamdy Abdala Elnagar, Wael Mohamed Wafa*, Abdelaziz Mustafa Sakr, Mohammed Mahmoud Hegazy
...s of testosterone (TES), leptin, and prolactin (PRL) in the blood and their relationships with age advancing of Egyptian buffalo males from one up to 24 month of age. Blood samples were taken from 66 male buffalo calves at 1, 3, 6, 12, 18 and 24 month of age (11 animals at every age). TES, leptin and PRL levels were determined in blood plasma. Results showed insignificant increase in TES and PRL by age advancing at 1-3 month...
Aysam Fayed1, Mohga A Ibrahem2, Soha A. Hassan3, Mohammed Abdalla Hussein4*, Tamer Roshdy1
...ermine glucose, insulin, leptin, TC, TG, HDL-C, ALT, AST, MDA, TNF-α, PCO. The HFD administrated rats resulted in increased total body weight, glucose, insulin, leptin, cholesterol, triglycerides, MDA, ALT, AST, TNF- α and PCO levels, as well as SREBP1 gene expression, according to the findings. However, our findings revealed a significant reduction in HDL-C, GSH, CAT and PON 1 enzyme levels, the expression of th...
Zheng-Yong Wen1, 2*, Chuan-Jie Qin1,2, Bin Li1,2, Rui Li1,2 and Xiao-Tao Shi3*
... In the present study, a leptin gene was characterized from the darkbarbel catfish (Pseudobagrus vachellii) and its expression patterns in response to different feeding status were investigated. The cDNA of the pvleptin was 1186 bp long, containing a 519 bp open reading frame (ORF) that predicted to encode a protein of 172 amino acids. Multiple Leptins alignment showed that four a-helix do...
Ting Jia1*, Dong-Min Hou2 and Wan-Long Zhu2*
...ing thermogenesis (NST), leptin levels and hypothalamic neuropeptide gene expression were measured in each group. The results showed that body mass in A. chevrieri was significantly affected by temperature, food and photoperiod, which was decreased by low temperature, food restriction and short photoperiod. RMR and NST were significantly affected by temperature and food quantity. The content of leptin was significantly affec...
Meltem Kızıl1*, Ali Rişvanlı2, Murat Abay3, Tarık Şafak4, Mehmet Akif Kılınç5, Öznur Yılmaz6, Burak Fatih Yüksel1 and İbrahim Şeker1
...ermine irisin, asprosin, leptin, adiponectin, and IGF-1 levels in cows and calves after calving according to the mode of delivery. The study was carried out with 20 Holstein cows and 20 calves born from these cows. Blood samples were taken from cows and calves in all groups during birth, after drinking colostrum from calves and on the 15th, 30th, 45th and 60th days after birth in 10 ml tubes. The levels of the aforementioned molecules in these blood samples we...
Desak Nyoman Dewi Indira Laksmi1*, I. Gusti Ngurah Bagus Trilaksana1, I. Wayan Sukernayasa1, Nyoman Oka Widiarta2, I. Wayan Nico Fajar Gunawan1, I Made Merdana3
... study aims to show that leptin can increase the estrus intensity and the appearance time of postpartum estrus in primiparous cattle. This is a true experiment using a Randomized Pre Post Group Control Design. Furthermore, the leptin administration and observations of the estrus appearance in Bali cattle were conducted at SIPADU and the Breeding Center in Sobangan Village, Mengwi District, Badung Regency. The results showed ...
Nesreen Ahmed Nasser1, Anas H. Sadek2, Bayadir Abdulhussein Mahmeed3, Osama Akram Mohsein4*
...state cancer antigen and leptin in patients with prostate cancer and their role in the development of the disease. Methodology; The study included 35 men suffering from prostate cancer and 35 healthy men as a control group. Samples were collected at Al-Kadhimiya Hospital for the period between 1/11/2023 and 1/3/2024, and 5 ml was withdrawn from each participant and placed in a gel tube. prostate-specific antigen (PSA) and leptin...
Al-Moataz Bellah Mahfouz Shaarawy1, Mahmoud Yassin Mohamed1*, Mahmoud Sayed Sayah2,1, Ashraf Ali Mehany1, Ezzat Arafa Ahmed El-Beltagi1, Shimaa M. Ali1
...e growth rate reflecting leptin (LP) and growth hormone (GH) levels, is a route for forecasting the performance of later growth and reproductive traits in Friesian calves. thirty calves (15 males, and 15 females), were categorized into three equal groups. The 1st group (n=5 males and 5 females), which recorded the lowest values from GH, and LP at weaning (105 d) considering then the average daily gain (ADG) from birth to weaning in each animal; 2nd group that ...
Suroor Hafedth Mohammed, Tahreer Mohammed Al-Thuwaini*
...le adipokines, including leptin, and visfatin. The expression and/or secretion of adipokines could play a role in regulating fertility. Thus, this study aimed to investigate the association of litter size with the adipose tissue biomarkers in Awassi ewes. In the current study, 100 sexually mature, not pregnant or lactating, and healthy ewes between the ages of 3 and 4 years were evaluated. The live body weight and age of each animal were determined. Serum was ...
Tamadhur H. Hussein, Layth H. Merzah, Tahreer M. Al-Thuwaini*
...dipose tissue, including leptin and visfatin. Adipokines increase energy levels and stimulate the production of essential reproductive hormones to enhance reproductive activity in livestock. Therefore, this study examined the relationship between litter size and adipokines in Hamadani ewes. This study examined 140 ewes aged between 3 and 4 years, which were sexually mature, not pregnant or lactating, and healthy. Live body weight, age, and body measurements we...
Sana Eijaz, Asmat Salim* and Mohammad Anwar Waqar
...of serum adiponectin and leptin. Our data suggests that the antidiabetic activity of these herbs may be due to the action on insulin signaling genes and adipokines level along with the normalization of blood glucose and body weight. These herbs may offer a safe and economic strategy and has nutritional significance for the cure and prevention of type 2 diabetes....
Pakistan Journal of Zoology
November
Featuring
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Effects of Recombinant Porcine Epidermal Growth Factor on Diarrhea, Growth Performance and Intestinal Development in Healthy and Piglets with Enteritis
Wenjun XU, Fenghua Li, Yanan Wang, Wei Zhou, Bingbing Xia and Jun Zhao
Pakistan J. Zool., Vol. 57, Iss. 2, pp. 689-699
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Blood Transcriptome Analysis Indicates Age-Associated Differences in Immune-Related Gene Expression in Captive South China Tigers (Panthera tigris amoynesis)
Qunxiu Liu, Yingying Wang and Yaohua Yuan
Pakistan J. Zool., Vol. 57, Iss. 2, pp. 689-699
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Effect of Acacia nilotica Against Nephrotoxicity Induced by Gentamicin in Rat: Role of Antioxidants, Anti-Inflammatory and Antiapoptotic Markers
Saed A. Althobaiti, Safa H. Qahl, Layaly Elsigar, Lobna M.A. Gurafi, Zeinab Kanani, Mohamed Mohamed Soliman and Omaima Nasir
Pakistan J. Zool., Vol. 57, Iss. 2, pp. 681-688
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Molecular Diagnosis of Theileriosis and Associated Risk Factors in Captive Cervid and Antelope of Punjab, Pakistan
Muhammad Azhar, Muhammad Hassan Saleem, Muhammad Ijaz, Ayesha Safdar and Kamran Ashraf
Pakistan J. Zool., Vol. 57, Iss. 2, pp. 671-680
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