Effect of Angong Niuhuang Pills on Positive Mental Symptoms Caused by Acute Lacunar Infarction in Patients with Mild Alzheimer
Effect of Angong Niuhuang Pills on Positive Mental Symptoms Caused by Acute Lacunar Infarction in Patients with Mild Alzheimer
Haixiao Zhang1, Xilong Yang2, Yinfeng Li3, Binyu Xu4, Juan Du2,5, Ronghua Wu6 and Sangsang Xiong2*
ABSTRACT
The aim of this study was to explore the effect of angong niuhuang pills (ANP) on positive mental symptoms caused by acute lacunar infarction in patients with mild alzheimer (MA). A total of forty patients with MA from our hospitals between December 2021 and November 2022 were assigned by the Richmond Agitation and Sedation Scale (RASS) assessment into a control group (CG) and a treatment group (TG). Both groups were given a sedative treatment scheme for on-demand use in blind method. The TG was given ANP orally or nasal feeding. Then, the duration of course disease of the two groups of patients was observed. Statistical analysis was performed on the duration of the disease (numbers of half days, half day = 12 h) and the correlation of other data between the two groups. The duration of disease in the TG was shorter than that in the CG (P<0.05). ANP can shorten the duration of the disease course of positive psychiatric symptoms caused by acute cerebral infarction of MA (the infarction site has no anatomical correspondence with the psychiatric symptoms), and contribute to start rehabilitation training early and improve the prognosis of the disease.
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