Mehmet Guvenc1,*, Ayşe Nilay Guvenc3, Ökkeş Yılmaz2 and Mehmet Tuzcu2
...his study, the effect of resveratrol on the liver of rats induced by fructose was investigated. Adult male Winstarrats were randomly divided into four groups; control, resveratrol, fructose, and resveratrol plus fructose. Resveratrol was administered 30 mg/kg intraperitoneally. Fructose (10% w/v) was administered with drinking water for 56 days every alt...
Zijuan Li1,2, Rong Ma2, Muhammad Khan3*, Chenchen Liu2, Xiaolin Cui2 and Yongming Li1,2*
...ally occurring analog of resveratrol has been shown to exhibit anticancer activity in various human cancer cells. However, the anticancer mechanism of piceatannol is not well studied. In the meantime, cisplatin (CDDP) is the first line treatment for some tumors. The present study was aimed to explore the cellular targets and anticancer mechanism of piceatannol in human osteosarcoma U2OS cells. Cell proliferation was measured using CCK-8 assay and colony formin...
Muhammad Sajid Hamid Akash1*, Hina Sharif1, Kanwal Rehman2, Sumbal Rasheed1 and Shagufta Kamal3
...therapeutic potential of resveratrol (RSV) to treat ATO-induced metabolic disorder. Twenty Wistar rats were used for this study; one group was normal control (NC), second group was exposed to ATO only while the other two groups received metformin (MF) and RSV separately along with ATO. We measured serum levels of glycemic index biomarkers and carbohydrate metabolizing enzymes. Simultaneously, we also measured arsenic concentration in liver using HG-AAS techniq...
Atilla Yıldız* and Ayse Kılıç
...d to investigate whether resveratrol influences in repeat breeder cows on the conceiving. Treatment and control group consisted of 12 cows. Two doses of prostaglandin F2 alpha were administered intramuscularly 11 days apart. Treatment group was given 500 mg resveratrol once daily from the administration of the second prostaglandin F2alpha to the insemination day. Control group did not receive resvera...
Rusul Adnan Dawood, Hasan F.K. Alghetaa*
...without collaboration of resveratrol (RES) supplement. Forty-five adult Sprague Dawley, 8-10 weeks old female rats weighing 170-220 g were randomly grouped as following; control group (C) kept without any medication. Dimethyl sulfoxide (DMSO) used as vehicle to prepare RES treatment was given to D-group. RES administered to R-group. Challenge group of rats (HD) was administered HgCl2. The last group of rats (HR) was given HgCl2 with RES in the same doses menti...
Rabail Hassan Toor1,3, Raazia Tasadduq2, Jane B. Lian3, Janet L. Stein3, Gary S. Stein3 and Abdul Rauf Shakoori1*
...teoclast precursors, and resveratrol (RSV) as a standard for its anti-osteoclast activity. Upon RANK-L induction of RAW264.7 cells to differentiate into osteoclasts, we found 10ng/ml CQ-H as most efficacious concentration for inhibiting osteoclastogenesis with 57.8% inhibition of TRAP activity. Whereas, in comparison 20ng/ml RSV showed 49.9% inhibition of TRAP activity. Expression of osteoclast marker genes such as NFATc1, ACP-5, CTSK, MMP-9 and CTR corroborat...
Bushra AL-Khaqani, Amira Mohammed*
...natural substance called resveratrol, which is present in several plants, red wine, and grapes, has been researched for its potential anti-inflammatory, and antioxidant qualities, and to induce relaxation of airway smooth muscle. The current study investigated whether Resveratrol (RES) could lessen allergic asthma that ovalbumin (OVA) causes in rats. Current results revealed that RES improved significantly (P<0.05) allerg...
