Chukwuemeka Calistus Okolo1*, Ikenna Onyema Ezeh2, Chinelo Nnenna Uju3 and Nwakaego Ernestina Nweze1
...cts treatment outcome in trypanosomosis. Thirty-six rats randomly assigned to six groups (A--F) were used for the experiment. Supplementation with multi-strain probiotics was started in groups A--C from day 0 post-supplementation (PS). On day 7 PS all experimental groups (A--E) were challenged with 1x106 trypanosomes intraperitoneally except the uninfected control (F). When parasitaemia peaked, groups A and B received 7mgKg-1 and 3.5mgKg-1 of diminazene acetur...
Nurlan Akhmetsadykov1*, Tanatar Kydyrov2, Moldir Akhmetzhanova1, Gulnazi Akhmetova3, Maxat Berdikulov4
...tection and diagnosis of trypanosomosis. To create a recombinant antigen, bioinformatic analysis of the primary structure of T. evansi GM6 antigen from several regions was carried out. The protein sequence was reverse translated to the nucleotide sequence, after which the gene was synthesized using solid-phase method. The gene fragment, encoding the GM6 protein, was inserted or cloned into the pET28 expression vector after synthesis. The obtained sequences wer...
