Laila M. Fadda1, Nouf M. Al-Rasheed1, Iman H. Hasan1, Hanaa M. Ali2,3*, Nawal M. Al-Rasheed1,4, Musaed Al-Fayez5, Aly M. Ahmed5, Nada Almutlaq1, Nehal Qasem1 and Reem Khalaf1
Mustafa Cengiz1*, Jama Hussein Ali2, H. Mehtap Kutlu2, Djanan Vejselova2 and Adnan Ayhanci3
Yuanyuan Zhang1*, Liping Song1, Hui Guo2, Jun Wu1, Xiaoli Wang1 and Fangbin Yao1
...owth performance and the hepatoprotective and antioxidant effects of curcumin against carbon tetrachloride (CCl4)-induced liver injury in common carp Cyprinus carpio. A 10-week feeding trial was carried out. A basal feed was supplemented with 0 (control), 30, 60, 120 and 240 mg/kg curcumin to formulate five experimental feeds. At the end of the feeding trial, the growth performance was determined. Subsequently, CCl4 was used for th...
Asmaa Khamis1, Osama Abdalla1, Mohamed Hashem2, Noha Abdelnaeim1*
...hat are supposed to have hepatoprotective properties. This study aimed to compare the effects of both medicinal plant extracts on rats intoxicated with carbon tetrachloride (CCl4). A total of 60 male albino rats were equally distributed in six groups. The first group received purified water and was kept as a control. The second and third groups were given oral PN and PM (500 mg/kg/day) for 31 days, respectively. The fourth group was intraperitoneally injected ...
Bashir Ahmad1*, Ali Muhammad Yousafzai2, Waqar Ali1, Ikram Ilahi1, Farman Ullah3, Saeed Ahmad1, Ayaz Ali Khan1, Umair Ahmad2 and Hafsa Maria2
...with those of the common hepatoprotective medication silymarine (50 mg/kg body weight). When contrasted to toxic control rabbits, the highest dose of garlic aqueous extract i.e. 300 mg/kg b.w excellently decreased the high serum rates of alkaline phosphatase (ALP), alanine transaminase (ALT), and aspartate transaminase (AST). The outcomes of the extract-treated rabbits were comparable to those of the group of rabbits given silymarine. RBC, platelets, haemoglob...
Jawad Ali1,*, Samiya Rehman1, Aqsa Aslam1, Fouzia Tanvir2, Rida Liaqat1, Muhammad Ahmad1, Aamir Riaz1, Muhammad Shafique3, Hassan Ali1 and Amjad Ali1
...es imparts antidiabetic, hepatoprotective, hypolipidemic, antidepressant, immunosuppressive, anti-microbial properties to the W. coagulans Dunal. Plant samples from Mianwalli, Kohat, and Sargodha city were gathered for antioxidant potential determination. Free radical scavenging activity and total antioxidant activity experiments were performed on the samples using the DPPH and Phosphomolybdenum methods. Results shows leaves extract from Mianwali has the highe...
Mustafa M. Khalaf*, Rana A. Salih
...ion of quercetin’s hepatoprotective effects against cyclophosphamide-induced hepatotoxicity. Twenty-eight male Westar rats (that weighed 200–250 g) were chosen at random and divided into four equal groups for this investigation. During the initial periods of acute exposure, the animals had treatment with quercetin (50 mg/kg) for 30 days on consecutive days. Cyclophosphamide (100 mg/kg) was administered intraperitoneally only on 10 and 30 days six h...
Usama Mahalel1, Barakat M. Alrashdi1, Ibrahim Abdel-Farid1, Sabry El-Naggar2, Mohamed Hassan3, Hassan Elgebaly1 and Diaa Massoud1,4*
Suhad Mohmmed Alrobyrai1 , Falah Muosa Al-Rekabi2*
... This study explored the hepatoprotective effects of Alpha Lipoic Acid (ALA) and Tempol against subacutely repeated acetaminophen (APAP) exposure in a murine model. Fifty male Balb-c mice were divided into five groups. Groups received 700 mg/kg.BW of APAP and oral treatments: G1 (distilled water, negative control), G2 (no treatment, positive control), G3 (Par+Tempol, 20 mg/kg.BW), G4 (Par+ALA, 20 mg/kg.BW), G5 (Par+Tempol+ALA, 10 mg/kg.BW each). Half animals w...
Afrah Adil Hassan1*, Hawraa F. H. Alowaid1, Majdy Faisal Majeed2
SHAHIDA NAVEED,BARKATULLAH,MUHAMMAD IBRAR
Tamara Natik Dawood*
...al properties, including hepatoprotective, antioxidant, anti-inflammatory, anticancer, and cardioprotective effects. The study aims to determine the influence of several levels of silymarin on the productive and biochemical parameters in local lambs. A total of 30 lambs are classified into three groups. G1 (ten lambs) received Silymarin (420 mg/kg) orally, G2 (ten lambs) received Silymarin (210 mg/kg) orally, while G3 (ten lambs) received distal water (control...
Tahani Ahmad Al-Matrafi1, Zuhair M. Mohammedsaleh2, Mamdoh S. Moawadh2, Waheeb S. Aggad3, Rawabi Mohamed almuhimed4, Zamzam Alhuwaymil5, Aishah E Albalawi6, Ifat Alsharif7, Hailah M. Almohaimeed8, Fatima S. Alaryani9 and Mona H. Soliman10,11*
...dy aimed to evaluate the hepatoprotective effects of aqueous, methanolic, and ethanolic extracts of Tamarix dioica leaves against paracetamol-induced toxicity. In this study, 36 albino mice were randomly grouped into six groups, each consisting of six mice: Group I (normal control), Group II (paracetamol-toxified), Group III (positive control with Silymarin @ 200 mg/Kg), Group IV (aqueous T. dioica extract @ 400 mg/Kg), Group V (methanolic T. dioica extract @ ...
Hina Abrar1*, Hina Yasin1, Hira Naeem2, Rabia Bushra1, Shaukat Mahmood2 and Kaneez Fatima3
... possess the significant hepatoprotective effects owing to the reduced blood flow. Therefore, the present study was aimed to evaluate the hepatotoxicity of PHY alone and in combination with PRL in healthy male rabbits. Post treatment level of various liver enzymes including alanine transaminase (ALT), alkaline phosphatase (ALP), gamma-glutamyltransferase (γ-GT) and bilirubin (BRB) were measured and compared with the normal values. Additionally, histologi...
Abeer S. Hafez1, Shereen M. Aly1, Dalia M. A. Elmasry2*, H. A. Hussein3, Marwa A. Abdelmagid4
...ion, immunostimulant and hepatoprotective effect. Nanopropolis is a natural nanomaterial that could be used to improve the properties of propolis to be easily applied. Propolis nanoparticles are easily absorbed and have better antibacterial and antifungal effects than ordinary propolis. The present study aimed to compare propolis ethanolic extract (PEE) and propolis nanoemulsion (PN) as a feed additive in poultry farms by evaluating their influences on growth,...
