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Analysis of Genomic DNA Methylation in Six Tissues of the Greater Horseshoe Bat (Rhinolophus ferrumequinum)

Analysis of Genomic DNA Methylation in Six Tissues of the Greater Horseshoe Bat (Rhinolophus ferrumequinum)

Sen Liu1,2, Yue Zhu2, Haixia Leng2, Ying Wang1, Xiangju Yin1 and Yajun Zhao1*

1Institute of Resources and Environment, Henan Polytechnic University, Jiaozuo 454000, Henan, China
2Jilin Key Laboratory of Animal Resource Conservation and Utilization, Northeast Normal University, Changchun 130024, Jilin, China.
 
Sen Liu and Yue Zhu have made equal contribution.

*      Corresponding author: [email protected]

Fig. 1.

Methylation levels in six tissues of R. ferrumequinum. Data are presented as the mean ± SE. Asterisks indicate significant differences: **, p < 0.01; *** p < 0.001.

Fig. 2.

Epigenetic differentiation among six R. ferrumequinum tissues. (a) Clustering tree based on Nei’s unbiased epigenetic distance matrix. (b) Between-group eigen analysis using PCA values based on the epigenetic covariance matrix; the F1 and F2 axes explain 77.3% of the total variance (p < 0.001).

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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