Clinical Effect of Yiqi Huoxue Tongmai Decoction in the Treatment of Diabetic Peripheral Neuropathy
Clinical Effect of Yiqi Huoxue Tongmai Decoction in the Treatment of Diabetic Peripheral Neuropathy
Genlong Zhan1*, Yunhua Zheng2, Desheng Li*4 and Hongmei Zhang3
ABSTRACT
The objective of this study was verify the effects of Yiqi Huoxue Tongmai Decoction on patients with diabetic peripheral neuropathy (DPN). A total of 130 patients with DPN who were treated in our hospital from January 2015 to July 2016 were selected and randomly divided into a control group and a treatment group, with 65 cases in each group. The control group was treated with conventional western medicine, and the treatment group was treated with self-made Yiqi Huoxue Tongmai Decoction. The efficacy of both strategies was evaluated with clinical symptoms, nerve reflex, electromyography, nerve conduction velocity, and hemodynamics. We found that the number of markedly effective cases in the treatment group was higher than that in the control group. The total effective rate was 89.23% in the treatment group and 72.31% in the control group. The total effective rate in the treatment group was higher than that in the control group (P<0.05). The whole blood high shear viscosity, whole blood low shear viscosity, plasma viscosity, as well as erythrocyte aggregation index of both groups decreased after treatment compared with the pre-treatment baseline. The hemorheological indexes of the Yiqi Huoxue Tongmai decoction group were lower than those of the control group. To conclude Yiqi Huoxue Tongmai Decoction has significant clinical effect in the treatment of DPN, can effectively improve the blood rheology of patients, and has the advantages of simplicity and high safety.
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