Effect of Silnultaneous Vaccination with the Bivalent Foot and Mouth Vaccine and Bovine Ephemeral Fever Vaccine on the Immune Response OF Cattle
Effect of Silnultaneous Vaccination with the Bivalent Foot and Mouth Vaccine and Bovine Ephemeral Fever Vaccine on the Immune Response OF Cattle
Attyat, M. Kotb; Abeer, E. Mansour; Naglaa, I. Aly; Zeinab, T.Salama and Azab, A. Mohamed
ABSTRACT
The present study was aimed to evaluate the vaccination of cattle against bovine ephemeral fever (BEF) and bivalent foot and mouth disease (FMD) strain O and strain A. so fifteen calves, six month old, were vaccinated singly and simultaneously and two calves were left as none vaccinated control. The serum neutralizing antibody titer expressed in log10 of FMD (strain O and strain A) in calves vaccinated with bivalent FMD vaccine only were increased from (0.9 log10 and 0.9 log10) consequently at the first week post vaccination (WPV) till it reached (2.7 log10 and 2.85 log10) for type O and type A respectively by the week. These titers were reduced to (l .2 log10 — 1.35 log10) by the 16th WPV. The FMD neutralizing antibody titer in calves vaccinated simultaneously with bivalent FMD and BEF showed increase in the titer from the 1 st WPV till reached the highest titer in the WPV (2.55 logto and 2.7 logto) for type O and type A, then decline to (1.2 log10 — 1.35 log10) by the le WPV. Determination of BEF serum neutralizing antibodies in calves vaccinated with BEF only showed an increase in the titer from (0.15 log10) from 1 st week till reached its peak after 8 weeks (1.8 log10), while in calves vaccinated simultaneously with BEF and FMD the serum neutralizing antibody titer reached to 1.85 log10 by the 8th week. Evaluation of the cell mediated immunity for both FMD and BEF in vaccinated calves revealed that such immune response was started to increase from the 3rd day post vaccination (DPV) and reached its peak at 21 - 28 (DPV). So, simultaneous vaccination of calves with the bivalent FMD and BEF could be considered of applicable benefit.
To share on other social networks, click on any share button. What are these?
