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Immune Response of Pregnant Mares and Their Foals for Inactivated Equine Influenza Vaccine

Immune Response of Pregnant Mares and Their Foals for Inactivated Equine Influenza Vaccine

Ebied, Eman M.; Salem, Zeinab T. and Al-Imam, Hemmat S.

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo.

ABSTRACT

This study comprises the immune response of pregnant mares and their foals to monovalent inactivated freeze-dried equine influenza (El) vaccine, reconstituted in diethylaminoethyle (DEAE) Dextran solution as an adjuvant. It was found that mares developed high haemagglutinating inhibition (HI) titre at 3 weeks post vaccination and remain with protective level up to 6 months, while their foals had moderate (HI) antibodies within  48 hours post colostral suckling, the HI antibodies rise to a level similar to their dams within one to two weeks then persisted with considerable level up to 6 months of their age.

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