In Vitro and In Vivo Acaricidal Activity of Senna alata Leaves Extract Against Rabbit Ear Mites, Psoroptes cuniculi
In Vitro and In Vivo Acaricidal Activity of Senna alata Leaves Extract Against Rabbit Ear Mites, Psoroptes cuniculi
Nur Athiqah M.Y*, Nur Elisa S, Muhammad Erfan Faiq Y, Ghazali M.F, Chai M.H, Lananan F.
ABSTRACT
In this study, the effectiveness of Senna alata leaf extract against rabbit ear mites, Psoroptes cuniculi, was evaluated using both in vitro and in vivo methods. The results demonstrated a clear correlation between the extract concentration and mite mortality rate. Higher concentrations of the extract in vitro resulted in increased mite mortality, with specific concentrations causing 50% (LC50) and 90% (LC90) mortality identified as 282.45 mg/ml and 478.71 mg/ml, respectively. In vivo tests showed significant reductions in mite infestation with extract concentrations of 160 mg/ml and 200 mg/ml. The 200 mg/ml concentration exhibited slightly higher efficacy compared to 160 mg/ml. The mean infestation level decrease for concentration of 200 mg/ml from 2.5 ± 0.4 on Day 0 to 1.05 ± 0.23 by Day 7. These findings indicate that S. alata leaf extract has strong acaricidal properties and could potentially serve as a natural and sustainable alternative to synthetic acaricides for managing rabbit ear mite infestations.
Keywords | Biopesticide, Ear mange, Gelenggang, Phytochemicals, Sustainable, Terengganu
To share on other social networks, click on any share button. What are these?
