Redressal of Antibiotic Resistance using Plant Extracts
Adeen Kiran1, Umar Farooq Gohar1*, Ayesha Farooq1, Malik Muhammad Asif2 and Hamid Mukhtar1
ABSTRACT
With the passage of time antibiotic resistance is prevailing in microbes and current drugs are not effective enough to cure infectious diseases caused by these resistant pathogens. In this battle, there is a continuous need to develop new drugs or compounds that can cure these infections or to reverse the antibiotic resistance in these pathogens. In recent years different experimental approaches highlighted the importance of phytochemicals present in plants and its ability to kill these pathogens and microbial inability to develop resistance against these pathogens. Therefore, the trend has been shifting from using synthetic or semi-synthetic antibiotics to the use of medicinal plants which are the part and parcel of traditional medicines. Thus, this review article explains the different mechanisms adopted by microbial life to develop resistance against antibiotics. This article also explains how the resistance can be reversed as well as the bio-medicinal importance of plants and their effectiveness against many pathogens.
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