Study of the Relationship of Vitamins B12 Deficiency and Effect on Children
Study of the Relationship of Vitamins B12 Deficiency and Effect on Children
Noor Nemia Hafed
ABSTRACT
The term “vitamin B12” refers to a particular class of cobalt-containing corrinoids that have biological activity in humans. Cobalamins are another name for this class of corrinoids that are biologically active. The commercially available version of vitamin B12 used in food supplements and food fortification is called cyanocobalamin. The primary cobalamins found in foods are hydroxo-, methyl-, and 5’-deoxyadenosyl-cobalamins.Some processed foods may include sulphitocobalamin, which has a sulphite ligand chelated to the central cobalt atom in the corrin ring. One of the most prevalent vitamin deficiencies is a vitamin B12 insufficiency. It occurs more frequently in underdeveloped nations. In fact, 40% of children are affected by it. Methods: There were 30 sick children and 30 healthy children among the pediatric patients that were admitted to the hospital throughout a 4-month period (April 2022 to July 2022). Each patient’s case information was collected and recorded. Whereas the results of the peripheral smear were used to identify vitamin insufficiency. levels, leukocyte in complete blood count, hemoglobin (Hb), mean erythrocyte volume (MCV), platelet values and ferritin. Results: Vitamin deficiency B12 in children is considered very common in children because children are picky about their food, so if it is not diagnosed in a timely manner, it has long-term repercussions. It causes unidentified neurological, respiratory, gastrointestinal, or other problems. The results of the tests discussed in this research show that there is a significant difference between sick and healthy children. Conclusion: The findings demonstrated that children with vitamin B12 deficiencies, particularly young children, which is a significant issue that most children experience. Causes anemia, poor motor development, and severe nerve damage. This disease has been seen to spread in low-income countries where the majority of children are malnourished and vitamin B12 is required to create red blood cells and participate in the synthesis of RNA that is deficient.
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