Unlocking the Medicinal Potential of Sarcococca saligna: Green Synthesis of Silver and Gold Nanoparticles for Enhanced Antibacterial and Antifungal Applications
Unlocking the Medicinal Potential of Sarcococca saligna: Green Synthesis of Silver and Gold Nanoparticles for Enhanced Antibacterial and Antifungal Applications
Sabi Ur Rehman1*, Laiba Arshad1, Saman Ali1, Shazma Massey2, Safeer Khan3, Abdul Samad4 and Fazal-Ur-Rehman5
ABSTRACT
A notable advancement in nanotechnology is the eco-friendly and cost-efficient production of metal nanoparticles utilizing botanical extracts. Silver nanoparticles are particularly noteworthy due to their potent antibacterial properties and relevance in nanomedicine. This study presents a green synthesis method using Sarcococca saligna leaf extracts to successfully produce both silver and gold nanoparticles. The formation and stability of the nanoparticles were verified through a change in physical colour and characterized using Ultraviolet-Visible spectroscopy and Scanning Electron Microscopy. Antibacterial and antifungal activity assessments revealed moderate efficacy against Candida albicans, Staphylococcus aureus and Escherichia coli, comparable to Amoxicillin and Fluconazole. Further discussion explores the antibacterial effects of Ag NPs, highlighting their potential applications in combating bacterial infections. These findings underscore the significance of green synthesis methods in nanoparticle production and their potential roles in various fields, including medicine and biotechnology.
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