Saima Younas and Aleena Sumrin*
...ated mutations (RAMs) to daclatasvir (DCV) in HCV GT-3a NS5A region in treatment naive and DAA treatment experienced patients, to understand their role in treatment failure. Patients samples and data was collected on prescribed questionnaire. Viral nucleic acid was isolated and amplified by gene specific primers followed by sequencing of NS5A region by Sanger method. Amino acid substitutions were identified by using Geno2Pheno tool. Hepatitis c virus genotype ...
Gehad M. Mohamed1*; Ahmed B. Barakat1; Marwa M. Gado1; Fatma M. Abdallah2
Novel Research in Microbiology Journal (2024), 8(1): 2320-2338
Saima Younas1*, Quratulain Maqsood1, Aleena Sumrin1, Muhammad Umer Khan2 and Nazim Hussain1
...As, sofosbuvir (SOF) and daclatasvir (DCV). Current study was designed to analyze treatment efficacy of two different DAA-based regimens in chronic HCV infected people among most recurrent genotypes (GT) of HCV in the patients employing DAAs for the first time (HCV treatment-naive) and in the patients those already experienced interferon (INF) plus ribavirin (RBV) combined treatment (HCV treatment-experienced).For this purpose blood samples were collected from...
