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Cytotoxicity and Molecular Docking Studies of a Novel Enaminone and its Cadmium (II) Complex

Cytotoxicity and Molecular Docking Studies of a Novel Enaminone and its Cadmium (II) Complex

Rahila Huma1,2, Tariq Mahmud1,*, Rubina Munir2, Sana Javaid Awan3,Kiran Iftikhar4 and Mufakkira-Tul-Islam5

1Institute of Chemistry, University of the Punjab, Lahore-54590
2Department of Chemistry, Kinnaird College for Women, Lahore
3The University of Lahore, Lahore
4Department of Chemistry, University of Gujrat (UOG), Gujrat
5Department of Chemistry, Lahore College for Women University, Lahore

*      Corresponding author: [email protected]

 

Fig. 1.

Scheme for the synthesis of the Enaminone PFA and its complex PFA-Cd.

Fig. 2.

Effect of concentration of PFA (A) PFA-Cd (B) and on MCF-7 line.

Fig. 3.

Selected binding pose of PFA with DNA double helix.

% Cell

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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