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Determination of Antimicrobial Potential of Economically Important Persimmon (Diospyros kaki) and Date Plum (Diospyros lotus)

Determination of Antimicrobial Potential of Economically Important Persimmon (Diospyros kaki) and Date Plum (Diospyros lotus)

Sundus Malik, Dawood Ahmad*, Irfan Safdar Durrani and Muhammad Sayyar Khan

Institute of Biotechnology and Genetic Engineering (IBGE), The University of Agriculture, Peshawar, Khyber Pakhtunkhwa, Pakistan.

 
*Correspondence | Dawood Ahmad, Institute of Biotechnology and Genetic Engineering (IBGE), The University of Agriculture, Peshawar, Khyber Pakhtunkhwa, Pakistan; Email: [email protected]

ABSTRACT

This study presents a preliminary investigation of the antimicrobial properties of various solvent extracts including aqueous, methanolic crude, ethyl acetate, hexane, and butanol from the dried leaves of Diospyros kaki and Diospyros lotus. The antimicrobial efficacy was assessed against four bacterial species and one fungal strain using a disc diffusion assay. The results indicated that the ethyl acetate and n-butanol extracts from the leaves of both Diospyros species exhibited significant inhibitory activities against all the tested microorganisms. Notably, the crude methanol extract of Diospyros lotus demonstrated the highest zone of inhibition (57%) against Escherichia coli. The ethyl acetate extract fraction of Diospyros kaki showed a strong inhibitory effect on E. coli (54%), while Diospyros lotus exhibited a slightly higher inhibition rate of 55%. Additionally, n-butanol extracts of both species displayed notable inhibition (52%) against E. coli and Pseudomonas aeruginosa. However, both E. coli and Staphylococcus aureus showed resistance to the n-hexane fraction from the leaves of Diospyros kaki. Moreover, P. aeruginosa was completely resistant to both aqueous and n-hexane fractions from both plant species. All leaf-extracted fractions from Diospyros kaki and Diospyros lotus exhibited considerable activity against Candida albicans, except for the n-hexane fraction of Diospyros kaki, which showed no activity. In conclusion, the leaf extracts of Diospyros lotus demonstrated greater antimicrobial potency compared to those of Diospyros kaki.

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Pakistan Journal of Zoology

November

Pakistan J. Zool., Vol. 56

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