Effect of Gross Saponins of Tribulus terrestris on IL-1β-induced Chondrocyte Injury by Regulating miR-99a Expression
Ji Xu, Zhonghua Liu, Zhenhai Cui and Wenhai Zhao*
College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China.
Fig. 1.
Effect of gross saponins of Tribulus terrestris on IL-1β chondrocyte apoptosis. A, Expression of apoptosis-associated proteins; B, Apoptotic flow pattern.
Fig. 2.
Effect of miR-99a overexpression on il-1β-induced chondrocyte apoptosis. A, Expression of apoptosis-associated proteins; B, Apoptotic flow pattern.
Fig. 3.
The effect of gross saponins of Tribulus terrestris (100 mg/L) on IL-1β-induced chondrocyte damage was reversed by inhibition of miR-99a. A, Expression of apoptosis-associated proteins; B, Apoptotic flow pattern.