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Effect of Calcium Supplement Combined with Carbetocin on Postpartum Hemorrhage in Scarred Uterine Cesarean Section

Effect of Calcium Supplement Combined with Carbetocin on Postpartum Hemorrhage in Scarred Uterine Cesarean Section

Guoqing Lai1*, Youxia Dai2 and Yuling Lan1

1Department of Obstetrics and Gynecology, Ganzhou Fifth People’s Hospital, Ganzhou 341000, Jiangxi Province, China
2Department of Obstetrics and Gynecology, Shangyou County People’s Hospital, Ganzhou 341200, Jiangxi Province, China
 
*      Corresponding author: [email protected]

ABSTRACT

Cesarean section (CS) in scarred uterus pregnancies (SUPs) is a high-risk obstetric procedure often associated with the risk of postpartum hemorrhage (PH). The objective of this study was to investigate the effect of calcium supplement combined with Carbetocin on PH after CS in SUPs. Data were collected from 112 patients with SUPs who underwent CS in the Ganzhou Fifth People’s Hospital from 2020 to 2022. Fifty-six patients received a treatment with calcium agents combined with Carbetocin (Comb group), and another fifty-six patients received a regular treatment (Regu group). The PH outcomes were compared between the groups and statistical analysis was performed. The PH volume in Comb group was substantially inferior to that in Regu group (P<0.05). The incidence of adverse reactions in Comb group was substantially inferior to that in Regu group (P<0.05). Additionally, Comb group had markedly shorter operation time and hospitalization time versus Regu group (P<0.05). Calcium agents combined with Carbetocin markedly reduced the incidence of adverse reactions and the amount of PH after CS in SUPs, and shortened the operation and hospitalization time. Hence, the combined application of calcium agents and Carbetocin in CS was recommended for SUPs to improve the prevention and treatment of PH.

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Pakistan Journal of Zoology

November

Pakistan J. Zool., Vol. 56

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