Analysis of High-Risk Factors of Stillbirth Among Pregnant Women in China
Analysis of High-Risk Factors of Stillbirth Among Pregnant Women in China
Xiaobo Wang1, Haiyang Tang2, Haizhen Dai2, Qingyi Xiang2, Jing Fang2 and Xiaoxia Bai2,3,4,5*
ABSTRACT
The objective of this study was to explore the high-risk factors of stillbirth after the two-child policy was fully opened. 327 cases of stillbirth were collected in the Obstetrics and Gynecology Hospital of Zhejiang University from January 2015 to December 2020. All cases were analyzed retrospectively, including general profile, high-risk factors of stillbirth in different years and different gestational periods. The incidence of stillbirth was 2.75%. The peak period of stillbirth during pregnancy was 28~28+6, 30~30+6, and 31~31+6 weeks, respectively. It remained at a low level after 38 weeks of pregnancy. The top 5 high-risk factors leading to stillbirth were umbilical cord factor, unexplained causes, maternal factor, fetal factor and placental factor. In 2015, unexplained causes, maternal factor and umbilical cord factor were the top three high-risk factors leading to stillbirth. Since 2016, umbilical cord factor, maternal factor and unknown cause have become the top three high-risk factors. Of all 327 cases, early stillbirth (28~36+6 weeks of gestation) accounted for 81.7%, with umbilical cord factor, maternal factor and unexplained cause as the top three high-risk factors. Late stillbirth (pregnancy≥37 weeks) accounted for 18.3%, of which umbilical cord factor, unexplained cause and maternal factor were the top three high-risk factors. The findings of this study emphasize on managing the complications in maternal pregnancy, strengthening prenatal fetal monitoring and terminating pregnancy timely, which may help to reduce the incidence of stillbirth.
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