Evaluation of Wound Healing and Anti-Oxidative Activity of Acacia Honey and N-Acetylcysteine in Sprague Dawley Rats
Evaluation of Wound Healing and Anti-Oxidative Activity of Acacia Honey and N-Acetylcysteine in Sprague Dawley Rats
Fatima Ali1*, Rimsha Tahir1 and Tahir Rehman Samiullah2
Effect of Acacia hony and N-Acetylcysteine on wound healing process on day 0, 3, 7, 9, and 14.
Effect of Acacia hony and N-Acetylcysteine on histological structure of skin during wound healing process in Sprague Dawley rats. Stain: hematoxylin–eosin. Magnification: × 20.
Effect of hony + NAC on hydroxyproline content in wound area of skin of rats. Values are presented as mean ± S.E.M; n = 9; *P<0.05, **P<0.01, and ***P< 0.001 compared to respective day control (honey) group.
(A) Effect of hony + NAC on gene expression profiling of treatment groups with PCR. (a) Honey group; (b) Honey+1% NAC group; (c) Honey+3% NAC group; (d) Honey+3% NAC group. (B) Gel band quantification by Image J.
Effect of hony + NAC on results of indirect ELISA for VEGF, IGF, SDF-1, CXCR-4 from skin proteins. Values are presented as mean ± S.E.M; n = 9; *P<0.05, **P<0.01, and ***P< 0.001 compared to respective day control (honey) group. ns mean non-significant.
