Harnessing CRISPR-Cas9 Gene Editing for the Eradication of Inherited Retinal Diseases in Purebred Dogs: A Path to Preservation and Health

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Harnessing CRISPR-Cas9 Gene Editing for the Eradication of Inherited Retinal Diseases in Purebred Dogs: A Path to Preservation and Health

Ali Sabeeh Ali1, Noor Abdulaala Kadhim2, Entissar Mansour Abdul Rasool3, Amran M. Al-Erjan4, Qais R. Lahhob5*, Mustafa Mudhafar6,7

Author Affiliations

1Department of Science, College of Basic Education, University of Sumer, Thi-Qar, Iraq; 2Department of Science, College of Basic Education, University of Sumer, Thi-Qar, Iraq; 3Department of Dentistry, College of Dentistry, Al-Iraqia University, Baghdad, Iraq; 4Department of Medical Laboratory Technology, Mazaya University College, Thi-Qar, Iraq; 5College of Health and Medical Technology, Al-Ayen University, Thi-Qar, Iraq; 6Department of Medical Physics, Faculty of Applied Medical Sciences, University of Kerbala, Karbala, Iraq, 56001; 7Department of Anesthesia Techniques and Intensive Care, Al-Taff University College, Karbala, Iraq, 56001.

*Correspondence | Qais R. Lahhob, College of Health and Medical Technology, Al-Ayen University, Thi-Qar, Iraq; Email: [email protected]

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Figure 1

Preservation of retinal structure in CRISPR-Cas9 treated dogs.

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Figure 2

Optical coherence tomography imaging reveals successful gene editing in inherited retinal disease.

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Figure 3

Improved retinal function in CRISPR-Cas9 treated group: electroretinography demonstrates enhanced photoreceptor and bipolar cell activity in inherited retinal disease.

This Issue

November 2024

Vol. 12, Sp. Iss. 1

Journal of Animal Health and Production

Harnessing CRISPR-Cas9 Gene Editing for the Eradication of Inherited Retinal Diseases in Purebred Dogs: A Path to Preservation and Health

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Harnessing CRISPR-Cas9 Gene Editing for the Eradication of Inherited Retinal Diseases in Purebred Dogs: A Path to Preservation and Health

Ali Sabeeh Ali1, Noor Abdulaala Kadhim2, Entissar Mansour Abdul Rasool3, Amran M. Al-Erjan4, Qais R. Lahhob5*, Mustafa Mudhafar6,7

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Journal of Animal Health and Production

Harnessing CRISPR-Cas9 Gene Editing for the Eradication of Inherited Retinal Diseases in Purebred Dogs: A Path to Preservation and Health

Special Issues

Membership/Association

Harnessing CRISPR-Cas9 Gene Editing for the Eradication of Inherited Retinal Diseases in Purebred Dogs: A Path to Preservation and Health

Ali Sabeeh Ali1, Noor Abdulaala Kadhim2, Entissar Mansour Abdul Rasool3, Amran M. Al-Erjan4, Qais R. Lahhob5*, Mustafa Mudhafar6,7

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