In vitro Antiviral Activity of Nigella sativa against Peste des Petits Ruminants (PPR) Virus

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In vitro Antiviral Activity of Nigella sativa against Peste des Petits Ruminants (PPR) Virus

Kiran Aqil¹, Muti-ur-Rehman Khan², Asim Aslam², Aqeel Javeed⁵, Rizwan Qayyum¹, Farooq Yousaf,¹ Farkhanda Yasmeen¹, Muhammad Luqman Sohail³ and Sajid Umar^4,*

Author Affiliations

¹Veterinary Research Institute, Lahore 54000

²Department of Pathology, University of Veterinary and animal Sciences, Lahore 54000

³University College of Veterinary and Animal Sciences, The Islamia University of Bhawalpur, Bhawalpur 63100

⁴Department of Pathobiology, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi 46000

⁵Department of Pharmacology, University of Veterinary and animal Sciences, Lahore 54000

* Corresponding author: [email protected]

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Fig. 1.

Effect of extract from N. sativa on morphological changes of Vero cell lines caused by Peste des Petit ruminants virus (PPRV). Microscopic view of the inhibition of N. sativa extracts on cytopathic effect (CPE) formation at about 96 h postinfection by PPRV. A, CPE of Vero cells infected by PPRV; B, Vero cells infected by PPRV and N. sativa extract (100µg/ml); C, Vero cells infected by PPRV and N. sativa extract (50µg/ml).

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Fig. 2.

Cell survival percentage for each dilution of of N. sativa extracts used for antiviral and cytotoxicity assay.

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December 2018

Vol. 50, Iss. 6, Pages 1999-2398

Pakistan Journal of Zoology

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In vitro Antiviral Activity of Nigella sativa against Peste des Petits Ruminants (PPR) Virus

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In vitro Antiviral Activity of Nigella sativa against Peste des Petits Ruminants (PPR) Virus

Kiran Aqil¹, Muti-ur-Rehman Khan², Asim Aslam², Aqeel Javeed⁵, Rizwan Qayyum¹, Farooq Yousaf,¹ Farkhanda Yasmeen¹, Muhammad Luqman Sohail³ and Sajid Umar^4,*

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In vitro Antiviral Activity of Nigella sativa against Peste des Petits Ruminants (PPR) Virus

In vitro Antiviral Activity of Nigella sativa against Peste des Petits Ruminants (PPR) Virus

Kiran Aqil1, Muti-ur-Rehman Khan2, Asim Aslam2, Aqeel Javeed5, Rizwan Qayyum1, Farooq Yousaf,1 Farkhanda Yasmeen1, Muhammad Luqman Sohail3 and Sajid Umar4,*

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Kiran Aqil¹, Muti-ur-Rehman Khan², Asim Aslam², Aqeel Javeed⁵, Rizwan Qayyum¹, Farooq Yousaf,¹ Farkhanda Yasmeen¹, Muhammad Luqman Sohail³ and Sajid Umar^4,*