Muhammad Usman Qamar1, 2, Sidrah Saleem1, Usman Arshad1, Muhammad Farhan Rasheed3, Hasan Ejaz4, Naveed Shahzad5 and Shah Jahan6,*
...including carbapenem and colistin proved to be most effective drug. Manuka honey manifested significant antibacterial activity against all test isolates with almost similar zone of inhibition (7.4mm) except E. cloacae. Highest MIC and MBC of manuka honey was observed against K. pneumoniae (30%v/v) while lowest against A. baumannii (20%v/v). Here, we conclude that Manuka honey possess potent antibacterial activity and might be used as an al...
Sahar Naz1, Farhan Rasheed2, Muhammad Saeed3*, Shagufta Iram4 and Ambereen Anwar Imran5
Imran Taj1,*, Ferhat Abbas1, Zafar Ahmad1, Mohammad Kamran Taj1, Deedar Ahmad2, Zahoor Ahmed2, Ghulam Mohammad2, Ajaz-ul-Haq1, Farooq Shahzad1 and Sabiha Azam3
...oxicillin, penicillin g, colistin sulphate, bacitracin and metronidazole. In lab animal trial C. perfringens type D affected the fore stomach, intestine, liver, kidney, pancreas and gall bladder of mice.
...
Sana Khan1, Raheela Taj1, Noor Rehman2, Asad Ullah3, Imad Khan3 and Sadeeq ur Rahman3,*
...vely, while, tygacil and colistin showed 100% susceptibility. On the other hands, 60%, 80%, 40% and 20% of metallo-β lactamase producers were found resistant to trimethoprim-sulphamethoxazole, levofloxacin, ciprofloxacin and piperacillin-tazobactam, respectively. Overall, current results show a high number of isolates resistant to commonly used drugs, and hence appropriate usage of antibiotics must be ensured to avoid further dissemination.
...
Amjad Ali, Kafeel Ahmad*and Shaista Rahat
...lin-tazobactam (76.47%), colistin (74.86%), ciprofloxacin (74.33%), piperacillin (72.19%), ceftazidime (68.98%), ofloxacin (68.44%), amikacin (66.84%), cefoperazone (66.31%), carbenicillin (66.31%), gentamicin (64.7%), tobramycin (64.7%), aztreonam (52.4%), ticarcillin (42.78%), ceftriaxone (32.08%), cefotaxime (15.5%), amoxicillin-clavulanic acid (6.41%). A total of 36.89% (n=69) isolates showed multi drug resistance. The MAR index of 34.22% (n=64) isolates w...
Aqsa Shahid1, Saima Muzammil1, Farhan Rasheed2,Bilal Aslam1, Muhammad Akhtar Ali3, Syed Zohaib Haider4, Masroor Ellahi Babar4, Muhammad Saeed1, Umair Waqas1 and Mohsin Khurshid1,*
...fluoroquinolones whereas colistin and tigecycline were the most active antimicrobial agents against A. baumannii as none of the isolates was found resistant to these two drugs. Moreover, the armA was found in 25% (n=37) of A. baumannii isolates which showed a high level of resistance to aminoglycosides i.e., amikacin; ≥256µg/ml (Breakpoints; ≥64µg/ml) and gentamicin; ≥MIC 64µg/ml (Breakpoints; ≥16µg/ml)....
Hend K. Sorour, Mohammed A. M. Saleh, Azhar G. Shalaby*
... As the extensive use of colistin, resistance has been increasing rapidly, thus, 200 different chicken samples were examined for isolation of E. coli and for colistin resistance gene. Eighty-three selected samples (chicken breast) were subjected to detection of colistin residues by HPLC (High-performance liquid chromatography). In this research, we used polymerase chain reaction (PCR) for ...
Pawinee Kingkan1, Thanathip Supcharoenkul1, Chaowit Rakangthong1, Chaiyapoom Bunchasak1, Komwit Surachat2,3, Wiriya Loongyai1*
...xture of amoxicillin and colistin (Amox-Co) and a basal diet supplemented with amoxicillin and 1 g/kg of a bacteriophage cocktail (Amox-Phage). Each treatment consisted of eight replicate pens, with 50 pigs per replicate. Average daily gain (ADG) and the FCR did not differ between the groups. The Amox-Phage group showed greater resistance to diarrhoea compared with the Amox-Co group during week 6 (p < 0.05). The Amox-Co group showed greater (p < 0.05) vi...
Md. Saiful Islam Siddiqui1*, Sharmin Akter2 and Mohd. Riajul Islam2
Mohamed Mahrous Amer1*, Hanaa Sayed Fedawy2, Hoda Mohamed Mekky2, Khaled Mohamed Elbayoumi2, Ahmed Ali El-Shemy3, Mohamed Abd El-Rahman Bosila2
... thickness. Doxycycline+ colistin combination helps in reduction of lesions in treat infected birds, with marked improvement in measured parameters. We recommended active actions to prevent causes and factors helping in including cellulitis, regular lowering bird density, enhancing restrict biosecurity, modulating the vaccination timing, improving management practices, as well as application of probiotics to improve and restore good gut health.
&nb...
Mohamed Ahmed Abaza1, Amany O. Selim2, Mona Abdallah3, Shimaa A.E. Atwa4, Hala El Daous5, Mona Abd-Allah Abd-Elrehim6, Mohamed M.S. Gaballa7, Reda R. Fathy1*
...ion dosage compared with colistin as commercial antibiotic at 5 days old. E. coli serotype O6 was the highest prevalent and pathogenic multi drug resistant bacterial strain.The assessment parameters were clinical signs, post-mortem lesions and histopathological picture which showed effective role of ZnO-NPs as bacterial inhibitor in the treated groups compared to control one. Quantitative analysis showed that ZnO-NPs significantly lowered gross lesion scores i...
Mohamed E. Enany1, Ahmed M. Hamouda2, Reem M. Khashaba3*
Mahesh Raj Pant 1 Dipti Shrestha 1 Shovana Thapa 2
Volume 2, Issue 3 May and June 2018 Pages 53-60
Shimaa, A. Abdel Salam1; Raghda, Hager2*
Novel Research in Microbiology Journal (2020), 4(5): 968-978
...study aimed to determine colistin susceptibility and to detect the presence of mcr-1 gene in the clinical isolates of GNB recovered from different clinical samples collected from Ain Shams University Hospital, Cairo, Egypt. About thirty-five GNB isolates were recovered from the different clinical samples that were collected during the period from February-April, 2019. These isolates were subjected to antibiotic susceptibility testing using disc diffusion assay...
Noha M. Mahmoud1*; Samah S. El-Kazzaz1
Novel Research in Microbiology Journal (2021), 5(6): 1415-1430
... The emergence of mobile colistin resistance (mcr) harboring microorganisms become of a health concern. Hence, screening for fecal carriage of Col-R Enterobacteriaceae could aid in the prevention and control efforts of Col-R. This study aimed to screen for Col-R Enterobacteriaceae in the stool specimens of the hospitalized patients; explore for colistin minimal inhibitory concentrations (MIC) and the genetic determinants of ...
Zine El Abidine Bzazou El Ouazzani1; Laila Reklaoui1; Houda Benaicha1,2; Said Barrijal1*
Novel Research in Microbiology Journal (2024), 8(4): 2491-2509
...t-resort options such as colistin, which is regarded as the last line of defense in treating multidrug- resistant (MDR) infections. This elevated level of resistance presents a substantial threat to the healthcare system, paving the way for a post-antibiotic era. In the present study, a checkerboard assay was employed to pinpoint the optimal combinations of Origanum majorana (OM) essential oil and colistin (CS) for the purpo...
Zine El abidine Bzazou El Ouazzani1*; Laila Reklaoui1; Monsif El Madany2; Houda Benaicha3; Said Barrijal1
Novel Research in Microbiology Journal (2024), 8(5): 2632-2652
...g cell death. Currently, colistin is regarded as a last-resort
antibiotic for treating infections caused by Gram-negative bacteria (GNB). Overuse of colistin
in animal feed and human medicine has led to the appearance of genetic mutations and the
acquisition of mobile colistin resistance (mcr) genes associated with colistin resistanc...
antibiotic for treating infections caused by Gram-negative bacteria (GNB). Overuse of colistin
in animal feed and human medicine has led to the appearance of genetic mutations and the
acquisition of mobile colistin resistance (mcr) genes associated with colistin resistanc...
Nguyen Hai Quan, Le Duc Thao, Nguyen Van Chao*
...ontrol (PCTL): added 1 g colistin per 1 kg of basal diet for first 3 weeks of age; and experimental treatments HE05, HE10 and HE15 in which 0.5 g, 1 g and 1.5 g of herbal extract mixture added in 1 kg of basal diet, respectively. The results showed that, growth performance, hematological indices were not affected by the addition of herbal extract mixtures in feed (p > 0.05). Fecal E. coli counts changed slightly with the bird age, however addition of herbal...
