Tasnim Farasat*, Saima Sharif, Farkhanda Manzoor, Muneeza Zafar and Shagufta Naz
...e prevalence of diabetic retinopathy and to evaluate its relationship with potential risk factors of diabetes on their first visit to a local hospital. Among the newly diagnosed diabetic subjects 33% (n=66) were with retinopathy. Out of which 30% (n=18) were male and 70% (n=48) were female. High density lipoprotein (HDL), both systolic and diastolic blood pressure, cholesterol level and serum insulin were significantly highe...
Zhipeng Song1,2, Jialiang Xin1,3, Xiaoli Wei1,2, Abula Zulipiya1,3, Kadier Kedireya1,2 and Xinmin Mao1,3*
... intervening in diabetic retinopathy. For in vivo experiment: 10 healthy db/m mice were used as the control group. Forty healthy db/db mice were randomly divided into the model, positive, ranibizumab and marein groups. There were 10 mice in each group. All mice were adaptively fed for one week. They were given the appropriate drugs by gavage. Tissue material was taken after 12 weeks. Haematoxylin-eosin (H&E) staining was used to detect the pathological cha...
Yunzhi Lin1, Jing He1, Xingwei Wu1* and Qian Shi2*
...ween proliferative vitreoretinopathy (PVR) and epithelial-mesenchymal transition (EMT) of Retinal pigment epithelium (RPE). The objective of this study was to investigate the role of AlkB homolog H5 (ALKBH5) in regulating EMT of RPE cells. Reverse transcription polymerase chain reaction (RT-qPCR) was implemented to determine the expression levels of ALKBH5, Zinc finger E-box binding homeobox 1 (ZEB1), insulin-like growth factor-2 mRNA-binding protein-1 (IGF2BP...
