Behzad Hussain1, 2, Abdullah Iqbal2, Muhammad Abubakar2*
Muhammad Saqib Shahzad1, Amina Arif1,*,Saeeda Kalsoom2, Javed Iqbal3, Shahnam Shafique2, Muhammad Shahid Nadeem4 and Rafique Ahmed5
...ffectiveness of combined ribavirin (RBV) and interferon (IFN) therapy in hepatitis C virus (HCV) patients. Overall, 590 HCV patients were evaluated pre and post combined drug therapy during the period 2015-2017. Distribution of HCV genotypes, age groups, viral load and alanine aminotransferase (ALT) values were recorded and analyzed for rapid virologic response (RVR), non-rapid virologic response (NRVR), sustained virologic response (SVR) and non-sustained vir...
Parakriti Gupta1, Kapil Goyal2 and Mini Pritam Singh3*
Hepatitis E Virus and Zoonosis
...is usually done, however ribavirin therapy has also shown a definitive role. There is upcoming literature on the role of sofosbuvir also in these groups of patients. Since the virus has only one serotype, univalent vaccine can provide protection against all HEV genotypes. Two vaccine candidates have been evaluated in clinical trials. Among these two vaccine candidates, one has been developed by Glaxosmithkline and another HEV 239 (Hecolin) has been developed b...
Hemeida, A. A., Osman, M., El-Shahat, Mohamed, Hashem, Medhat H., Mahmoud, Amal and Dahi, Hosni
...s (1801U/ml weekly) plus ribavirin (1000 mg for 75 Kg or 1200 mg for > 75Kg- Roche) and follow up by RT-PCR. The results showed that 67 patients (72.8%) responded to the treatment (group A), while 25 patients (27.2%) non responders (group B). The two groups were Screened for Serum alanine transaminase (ALT), Serum aspartate transaminase (AST), Serum alpha fetoprotein (AFP) , serum Albumin , serum creatinine , Serum TSH, Hemoglobin (Hb),White blood cells cou...
El.-Kadyl, M.A.S; Badr2, A.B.; zein3, Saiwa N. and Khalifa4, M.A.A.
Sabry Y. M. Mahmoud; Maher H. Hosseny and Mamdouh H. Abdel-Ghaffar
...lemented with or without ribavirin (RBV) •to examine its combination effect. With an electric shock treatments alone (5, 10 and 15 mA electric current), the replicates become PVY-free in rates53.8,72.7 and 87.5%, respectively. Simultaneous, RBV and electric shock had higher efficiency for PVY elimination, reaching rates of healthy plantlets of 66.7% with 5 mA, 90.0% with 10 mA, and 100.0% with 15 mA....
Gamal, Abdelaziz1*; Heba, A. Mostafa2
Novel Research in Microbiology Journal (2020), 4(3): 736-745
Adham Ezz El-Regal Mahmoud1, Atef Shoukry Sadik2 and Ahmed Mahdy3*
Saima Younas1*, Quratulain Maqsood1, Aleena Sumrin1, Muhammad Umer Khan2 and Nazim Hussain1
...ed interferon (INF) plus ribavirin (RBV) combined treatment (HCV treatment-experienced).For this purpose blood samples were collected from patients positive for anti-HCV antibodies, processed for RNA isolation, detection and quantification of HCV RNA, followed by GT determination. Treatment response rate was determined in terms of end treatment response rate (ETR) and sustained virological response rate (SVR) at end of treatment and 12 weeks after completion o...
Muhammad Shahid1, Iram Amin1*, Rabia Nawaz1,3, Samia Afzal1, Afza Rasul2, Muhammad Umer Khan4, Fatima Arshad Butt1 and Muhammad Idrees1
...ron with the addition of ribavirin. Analysis of variance (ANOVA) has been used for comparing variations in clinical data between patient groups. The clinical and virological data have been analyzed using correlation analysis. For the assessment of therapy response in patients, a binary logistic regression model has been used. ANOVA showed that differences in albumin %, AST/ALT ratio, and monocyte % between responders and non-responders have been statistically ...
