Shubhada K Chothe, Bhushan M Jayarao and Suresh V Kuchipudi
...develop novel anti-viral therapies....
Laila M. Fadda1, Nouf M. Al-Rasheed1, Iman H. Hasan1, Hanaa M. Ali2,3*, Nawal M. Al-Rasheed1,4, Musaed Al-Fayez5, Aly M. Ahmed5, Nada Almutlaq1, Nehal Qasem1 and Reem Khalaf1
...Q was the most effective therapies in the attenuation of liver injury assessed by a decrease in ALT and ALP activities down-regulation of Bax and CD68 expressions. It was concluded that the combination strategy of THQ and/or CUR may be considered as a potential antidote in combating liver injury induced by APAP due to their antioxidant effects with fewer side effects compared to NAC....
Anza Zahid*, Muhammad Ali Ayub, Mujtaba Saeed, Nasir Pasha, Abdul Jabbar Dar, Huzaifa Javed, Aimen Shakeel, Amna Nasir, Ana Akbar, Zainab Tarrar and Ayesha Humayun
...f the ailments and their therapies. ...
Madeeha Arshad1, Asmatullah1, Chaman Ara1, Shagufta Andleeb2 and Naveed Ahmad3,*
... antifolate used in such therapies. Current study was done to test the ability of TMP-SMX to induce developmental defects in mice fetuses. Different concentrations of the drug, 0.00, 4.10, 8.33 and 16.66 µg/g B.W. were administered orally to the dams on days 6-12 of gestation, and fetuses were recovered on day 18. Morphological observations of fetuses from 4.10, 8.33 and 16.66 µg/g B.W. dose groups showed abnormalities such as skin hemorrhages, mic...
Shaikh Abdul Lateef, Zhou Lin, Wu Jian, Junjie Qian, Jonathan Hartanto Tan and Zheng Shusen*
...d devise novel antiviral therapies to control the spread of hepatitis ...
Mahak Fatima1, Memoona Syed1, Rabia Zeeshan2, Farah Rauf Shakoori3, Naveed Shahzad4, Moazzam Ali1 and Zeeshan Mutahir1*
...mean to improve combined therapies for targeting drug-resistant cancers.
...
Yasir Sharif1, Saba Irshad1*, Ammara Muazzam1, Muhammad Hamza Tariq1, Ambreen Kanwal1, Sana Rasheed1, Mabel Baxter Dalrymple2 and Anam Tariq1
...ence to justify advanced therapies to overcome secondary complications, iron overload, disturbed hepatic and hematological profile of patients and overall offers insight into improving the quality of treatment for β-thalassemia major patients.
...
Asma Chaudhary1, Qurat-ul-Ain Ahmad1, Afia Muhammad Akram1, Sadia Roshan2 and Javed Iqbal Qazi3*
... effects of conventional therapies have caused researchers to explore alternate strategies, such as probiotics employment for disease control in aquaculture.
...
Amreen Zahra1*, Mushtaq A. Saleem2, Hasnain Javed3, Muhammad Azmat Ullah Khan4 and Abdul Rauf Shakoori4
...d antiretroviral regimen therapies....
Shaimaa A.Tawfik2,3, EL S.T. Awad1*, Hoda O.Abu Bakr1, Amira M.Gamal-Eldeen4, Esmat Ashour2, Ismail M.Ahmed1
...s one of the active chemotherapies for hepatocellular carcinoma. DOX-resistance is the cause of its limited use. Objectives: This study aimed to explore the influence of CSO on DOX-induced resistance and antioxidant status. Methods: 40 male albino rats weighing 150-200g were divided equally into four groups 10/each. CSO (5% w/w) were administrated oral daily for 30 consecutive days. DOX treated groups were injected IP at a dose of 2.5 mg/kg trice weekly to be...
Ahmad Shahzaib1*, Tabish Raza2 and Aisha Areej2
...use of immunosuppressive therapies, including cytokine blockade, JAK, and IL-6 inhibition in severely ill COVID-19 patients, is associated with increased secondary infections. Therefore, the current review aims to collect literature on the incidence of COVID-19 co-infections and immune-inflammatory responses to such infections. A better understanding of immune-inflammatory markers of COVID-19-associated coinfections is vital to advance COVID-19 treatment and m...
Abdulaziz A. Alaqil
... to avoid the antibiotic therapies, and simultaneously, maximize the broiler growth and health status, especially under EC challenge.
Keywords | Broiler chickens, Escherichia coli, Immune response, Productive performance, Propolis supplementation
...
Rabail Hassan Toor1,3, Raazia Tasadduq2, Jane B. Lian3, Janet L. Stein3, Gary S. Stein3 and Abdul Rauf Shakoori1*
...ive and safe alternative therapies for osteoporosis. Investigating the osteogenic potential of CQ, our research group previously reported osteogenic stimulatory effects of CQ (hexane fraction). The present study explores anti-resorptive effects of CQ-H on bones. We utilized RAW264.7 murine macrophage cell line as osteoclast precursors, and resveratrol (RSV) as a standard for its anti-osteoclast activity. Upon RANK-L induction of RAW264.7 cells to differentiate...
SHEIKH AJAZ RASOOL1*, MUNAZZA DANISH AJAZ2, MUHAMMAD SALMAN RASOOL3, AHSAN SATTAR SHEIKH4 & FIRDAUS KOUSAR BUKHARI5
...inding out non-classical therapies as reduction factors against Campylobacter nuisance in humans and poultry. In addition, a few probiotics have been instrumental to cut down the adverse effects rendered due to the classical antibiotic therapies with particular reference (wpr) to GIT. Particular probiotic strains (including Lactobacillus johnsonni La1 and Saccharomyces boulardii) have been able to downgrade the concentration...
Faiza Naeem1, Muhammad Farooq Sabar1, Muhammad Usman Ghani2,*, Qurat Ul Ain1 and Qurat-ul-Ain Zafar1
...geted drug discovery and therapies. An extensive study of published articles was conducted to enlist asthma-associated genes reported significant (P-value < 0.05) in the Pakistani population. Pathway Connector (http://bioinformatics.cing.ac.cy/PathwayConnector) was used to analyze the pathways associated with genes as well as novel pathways through complimentary network analysis. Protein-protein interaction studies were conducted using String (https://strin...
Sabry Y. M. Mahmoud; Maher H. Hosseny and Mamdouh H. Abdel-Ghaffar
...echnique using different therapies, such as thermo-, chemo- and electrotherapies. Potato plants cv. Diamond cultivated at Faculty of Agriculture farm, Sohag University were tested by direct antigen coatingenzyme linked immunosorbent assay (DAC-ELISA) using antisera against PVY, Potato virus X (PVX) and Potato leaf roll virus (PLRV). The results indicated the occurrence of single and mixed infections of three viruses in potat...
1*AFIRA WAQAR, 2ADNAN RAUF, 3BUSHRA CHAUDHRY &4IKRAM-UL HAQ
...ses. New pharmacological therapies may get established by understanding the underpinning of biological genetic effects. We focus here on the applications and strategies that are currently best suitable for genetic studies which provide preliminary genetic information for subsequent statistical analyses. Here we review the basic concept of genetic alterations including monogenic and polygenic characteristics of complex diseases to determine underlying genetic c...
Enany M.E.1, Fadel Hanaa M.2, Abo-Shama U.H.3, Ahmed Mona M.1, Kholief M.E.A.4*
...e efficacy of antibiotic therapies of human diseased animal model as felines and sheep infected with virulent H. pylori in seasons. A total of twelve H. pylori isolates cultivated from samples of stomachs and stool of felines, gastric and milk of sheep. These were previously confirmed by amplification of 16srRNA H. pylori to be detected by multiplex polymerase reaction against vacA, cagA, and hrgA and bio-typed based on urease and nitrate reduction testes, fin...
Praveen Reddy P., K. Sandhya and Aparna Srikantam*
...ermore, the conventional therapies are not effective for all patients with psychiatric disorders. Hence, alternative therapeutic strategies/agents are much needed. Clinical researchers suggest that certain microorganisms (beneficial microorganisms/probiotics) could be substituted for conventional therapies and/ or can be used in combination with current drugs. Such beneficial microorganisms which can influence the central ne...
Ahmed Ali1*; Ahmed I. Abd El-Mawgoud2; Al-Hussien M. Dahshan1; Azza A. EL-Sawah1; Soad A. Nasef3
Novel Research in Microbiology Journal (2019), 3(4): 415-427
...vering new antimicrobial therapies made vaccine the best choice to control E. coli infections in poultry farms. In this review, the various aspects of APEC infection in poultry with special focus on the epidemiology of APEC in Egypt in relation to virulence traits were discussed. In addition, the most recent vaccination trials against the APEC diseases in poultry were discussed. We concluded that the virulence gene patterns of APEC can be considered as molecul...
Radhika Baheti; Jayashri Mahore*; Vinita Patole
...s designed for probiotic therapies work on stabilizing the probiotics through several mechanisms; leading to a
significant number of probiotics that are available after passing through the various GI barriers, in addition to showing the desired therapeutic and/ or prophylactic effects. A brief critique of the health effects of probiotics, issues associated with their delivery, and the various formulation strategies employed to improve the probiotic tran...
significant number of probiotics that are available after passing through the various GI barriers, in addition to showing the desired therapeutic and/ or prophylactic effects. A brief critique of the health effects of probiotics, issues associated with their delivery, and the various formulation strategies employed to improve the probiotic tran...
Chronic infection: as an ecological model for emergence of the chronic obstructive pulmonary disease
Dmitriy V. Alekseev; Artem V. Lyamin; Karim A. Kayumov
...o propose more effective therapies in the future.
...
Gamal, Abdelaziz1*; Heba, A. Mostafa2
Novel Research in Microbiology Journal (2020), 4(3): 736-745
Ramesh Bhandari*; Fenyong Sun; Qiuhui Pan
Novel Research in Microbiology Journal (2020), 4(3): 746-765
...pment, and the antiviral therapies to cope with COVID-19 infection. Thus, the information and data gathered on coronavirus will be helpful in understanding all the aspects on SARS-CoV-2 virus, impact....
Apoorva Jain1; Ajay Kumar Oli1*; Sughosh Kulkarni2; Raghavendra D. Kulkarni2; Kelmani Chandrakanth3
Novel Research in Microbiology Journal (2024), 8(3): 2435-2451
... development of targeted therapies and preventive measures. Consequently, comprehensive efforts are needed aiming at unraveling the intricacies of antibacterial resistance in ESKAPE pathogens that are imperative to safeguarding the public health. The aim of the present review was to highlight the patho-mechanisms of ESKAPE bacteria towards the different antibiotics and genes involved in multi-drug resistance....
Jassim M. Khalaf Albozachri1*, Hameed A. AL-Timmemi2
...plete paralysis. Current therapies for spinal cord injury frequently show limited success. This study aims to clinically evaluate the effects of human placenta (HP) and adipose-derived mesenchymal stem cells (ADMSCs) on restoring spinal cord injuries in cats. Twenty-four adult healthy cats were randomly assigned to three equal groups (n = 8 each). Under aseptic conditions, the cats were anesthetized and underwent dorsal laminectomy with left lateral hemisectio...
Hu-Hu Chen1,2*, Jiao-han Zhou3 and Siat Yee Fong2,4
...development of effective therapies that address drug resistance and improve patient outcomes....
