Analysis of Clinical and Hematological Findings in Malaria Infected Patients in Hyderabad, Sindh
Analysis of Clinical and Hematological Findings in Malaria Infected Patients in Hyderabad, Sindh
Zarina Chang1, Nadir Ali Birmani1, Adil Hassan Chang2, Laraib Jamali2, Noreena Chang3 and Fouzia Chang4*
ABSTRACT
To investigate the effects of Plasmodium species on hematological parameters in a descriptive case study was carried out on malaria positive patients. The objective of the study is to determine how malaria disturbs complete blood cell parameters. If it is left untreated, it will only get worse and may even result in human death. Therefore, it is essential to observe blood cell parameters sensibly. In this observational study, the data has been collected from 220 malarial patients from Hyderabad Sindh. The diagnosis of malaria was confirmed by malarial test and complete blood count. The clinical and laboratory features were classified for statistical analysis. Out of 220 patients 76.36% had Plasmodium vivax, 20.90% had Plasmodium falciparum and only 2.72% had mixed infection. Not a single case of Plasmodium malariae and Plasmodium ovale were noticed. Males accounted for 124 cases (56.36%) of malaria specie, whereas females accounted for 96 cases (43.63%). Age wise estimation was highest 110 cases (50%) revealed from the age group of 1 to 10 years. Anemia was observed in 80% cases. In 75.45% of the patients had thrombocytopenia identified. Leukopenia was detected in 16.36% of cases, and leukocytosis was revealed in 12.72% of cases, while the WBC count was normal in 70.90% of cases. This study found that Plasmodium vivax cases were more than Plasmodium falciparum. This study suggests that in malarial cases anaemia, thrombocytopenia, leukocytosis, and leukopenia have been found to be the most prevalent haematological abnormalities.
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