Association of c.974C>G Mutation in Growth Differentiation Factor 9 with Recovery Rate in Peranakan Ongole Cattle
Irma1*, Siti Darodjah Rasad2, Nena Hilmia2, Cece Sumantri3
1Directorate General of Livestock and Animal Health Service, Ministry of Agriculture, Republic of Indonesia; 2Department of Animal Production, Faculty of Animal Husbandry, Universitas Padjadjaran, Sumedang, West Java, Indonesia; 3Department of Animal Production and Technology, Faculty of Animal Husbandry, IPB University, Bogor, Indonesia.
*Correspondence | Irma, Department of Animal Production, Faculty of Animal Husbandry, Universitas Padjadjaran, Sumedang, West Java, Indonesia; Email:
[email protected],
[email protected]
Figure 2:
Conserved region protein GDF9 Bos taurus; Sources: https://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi (Wang et al., 2023).
Figure 1:
Visualization of mutation point at p. 369 Trp>Arg and p.453His>Arg in GDF9 Bos taurus cattle. GDF9 and BMP15 interaction in both point mutations (p.369Trp>Arg and p.453Arg>His). (Caption: green color GDF9 protein, brown color BMP15, top circle: control GDF9, bottom circle: GDF9 mutant, black box: interaction area).
Figure 3:
Ligand intra- and extraovarian signaling and molecular pathways in follicle development (Figuiredo et al., 2018).
Figure 4:
Gene ontology of growth factor activity in biological processes.