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Association of c.974C>G Mutation in Growth Differentiation Factor 9 with Recovery Rate in Peranakan Ongole Cattle

Association of c.974C>G Mutation in Growth Differentiation Factor 9 with Recovery Rate in Peranakan Ongole Cattle

Irma1*, Siti Darodjah Rasad2, Nena Hilmia2, Cece Sumantri3

1Directorate General of Livestock and Animal Health Service, Ministry of Agriculture, Republic of Indonesia; 2Department of Animal Production, Faculty of Animal Husbandry, Universitas Padjadjaran, Sumedang, West Java, Indonesia; 3Department of Animal Production and Technology, Faculty of Animal Husbandry, IPB University, Bogor, Indonesia.

 
*Correspondence | Irma, Department of Animal Production, Faculty of Animal Husbandry, Universitas Padjadjaran, Sumedang, West Java, Indonesia; Email: [email protected], [email protected]

Figure 2:

Conserved region protein GDF9 Bos taurus; Sources: https://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi (Wang et al., 2023).

Figure 1:

Visualization of mutation point at p. 369 Trp>Arg and p.453His>Arg in GDF9 Bos taurus cattle. GDF9 and BMP15 interaction in both point mutations (p.369Trp>Arg and p.453Arg>His). (Caption: green color GDF9 protein, brown color BMP15, top circle: control GDF9, bottom circle: GDF9 mutant, black box: interaction area).

Figure 3:

Ligand intra- and extraovarian signaling and molecular pathways in follicle development (Figuiredo et al., 2018).

Figure 4:

Gene ontology of growth factor activity in biological processes.

Equation 1
Equation 2

Pakistan Journal of Zoology

December

Pakistan J. Zool., Vol. 56, Iss. 6, pp. 2501-3000

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