Bioinformatic Analysis of the Possible Mechanism of TOP2A Expression in the Development of Liver Cancer
Bioinformatic Analysis of the Possible Mechanism of TOP2A Expression in the Development of Liver Cancer
Man Wang1 and Fengmei Yang2*
The correlation between gene expression and clinical stages, gene methylation levels, and expression levels of TOP2A genes analyzed by different tools in tumor and normal tissues. A: GEPIA2; B: TIMER; C: Ualcan; D: The correlation between gene expression and clinical stages; E: methylation level.
Analysis of the correlation between immune cell infiltration and TOP2A expression (2A), the relationship between immune cell infiltration with different gene expression levels and prognosis (2B).
TIMER and GEPIA analyzed the correlation between gene expression and surface markers of immune cell.
Analysis of the correlation between TOP2A expression and clinical prognostic. A: OS; B: DFS; C: Survival probability.
Univariate and Multivariate analysis of prognosis in patients with liver cancer. A: OS; B: DSS; C: PFI.
Protein-protein Interaction network of TOP2A related proteins.
Expression of TOP2A protein in liver cancer tissue and normal tissue.
