Reporter Classical Swine Fever Virus: A Powerful Tool to Study Virus Biology
Reporter Classical Swine Fever Virus: A Powerful Tool to Study Virus Biology
Yongfeng Li, Mo Zhou, Xiao Wang, Libao Xie, Hua-Ji Qiu*
ABSTRACT
Classical swine fever virus (CSFV) is generally a noncytopathogenic virus in cell cultures. The development of reporter CSFV has provided an excellent option to directly detect viral replication without the use of secondary labeling. This mini-review discusses the applications of reporter CSFV in the study of CSFV biology, including efficiently screening the antivirals against CSFV and viral receptors, conveniently tracking the viral proteins in live cells as well as improving diagnostic methods and vaccines for classical swine fever.
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April 2016
Vol. 3, Iss. 2, Pages 24-46
