Deleterious Effects of Mercuric Chloride Toxicity Initiated Partially from Physiological Disorder of Kidney, Immunocytes and Redox System, can be Reversed by Resveratrol Administration
Rusul Adnan Dawood, Hasan F.K. Alghetaa*
Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq.
*Correspondence | Hasan F.K. Alghetaa, Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Baghdad. Baghdad, Iraq; Email: Kashifalkitaa@covm.uobaghdad.edu.iq
Figure 1:
Effect of resveratrol administration on the kidney function tests represented by blood urea levels. (n=5); *P<0.05.
Figure 2:
Resveratrol administration reversed the hepatotoxicity status in the experimental rats that were poisoned with mercuric chloride. Biochemical parameters of protein profile (A) Albumin concentration; (B) Globulin concentration; (C) Total Bilirubin. (n=5); *P<0.05, **P<0.01, ***P<0.001, #P<0.0001.
Figure 3:
Resveratrol treatment alleviated the oxidative stress mediated by mercuric chloride toxicity in TAC. (n=5), **P<0.01, ***P<0.001, #P<0.0001.
Figure 4:
Effect of resveratrol administration on the Peritoneal exudate infiltrating cells per animal of the study groups. (n=5); **P<0.01, #P<0.0001.