Determination of Anti-Mycoplasma capricolum Subsp. capripneumoniae Antibodies for the Sero-Prevalence of Contagious Caprine Pleuropneumonia in North-Western Pakistan
Determination of Anti-Mycoplasma capricolum Subsp. capripneumoniae Antibodies for the Sero-Prevalence of Contagious Caprine Pleuropneumonia in North-Western Pakistan
Faisal Ahmad1,2,3, Farhan Anwar Khan1, Hayatullah Khan4* and Muhammad Saeed1
ABSTRACT
Contagious caprine pleuro-pneumonia (CCPP) is a fatal disease of goats and causes enormous economic losses due to high morbidity and mortality. CCPP is enlisted as a notifiable animal disease by the World Organisation for Animal Health. The causative agent of CCPP is Mycoplasma capricolum subsp. capripneumoniae (Mccp). The present study aimed to investigate the seroprevalence of CCPP in north-western Pakistan. The study areas were divided into three zones: the northern zone, the central zone, and tribal zone. A total of 1300 serum samples were collected from November 2017 – April 2019 from goats of different ages and sex and were analyzed by monoclonal antibody-based cELISA. The analyses revealed two hundred twenty-seven (17.5%) samples positive for anti-Mccp antibodies. The zone-wise distribution of CCPP in goats was significantly different (P˂0.05), indicated by positive sera for Mccp of 23% animals from the northern zone followed by 15% and 13% from tribal and central zones, respectively. The data analysis showed non-significant values in the seroprevalence among bucks and doe(s), indicated by anti-Mccp sera from 16.6% bucks and 18.3% doe (s). Moreover, among different age groups, the prevalence of disease in adult goats (20%) was significantly (P˂0.05) higher than in kids (10.8%). It is evident from the present study that CCPP caused by Mccp is prevalent in Pakistan and both sexes of animals are equally susceptible to Mccp infection. Furthermore, the disease is more prevalent in the northern zone.
To share on other social networks, click on any share button. What are these?
