In Silico Analysis of Cu-Zn Superoxide Dismutase and Mn Superoxide Dismutase Genes in Fugu (Takifugu rubripes)
In Silico Analysis of Cu-Zn Superoxide Dismutase and Mn Superoxide Dismutase Genes in Fugu (Takifugu rubripes)
Mehtap Bayir*
The nucleotide sequence of the fugu sod1 gene. Exons of the sod1 gene are shown in capital letters and nucleotide position is indicated the numbers end the rows. The start site of transcription is indicated by +1. The 5’ upstream sequence, 3’downstream sequence and introns are shown in lower-case letters. A putative CAAT box, TATA box and polyadenylation signal (AATAAAA) are shown capital letters highlighted in yellow. The stop codon (TAA) is indicated by an asterisk.
The percentage of sequence identity and similarity among fugu sod1 gene and human, mouse, zebrafish, medaka sod1 and sod2 gene. The dots and dashes in the alignment represent sequence identity and missing amino acids respectively.
The nucleotide sequence of the fugu sod2 gene. Exons of the sod2 gene are shown in capital letters and nucleotide position is indicated the numbers end the rows. The start site of transcription is indicated by +1. The 5’ upstream sequence, 3’downstream sequence and introns are shown in lower-case letters. A putative CAAT box, TATA box and polyadenylation signal (AATAAAA) are shown capital letters highlighted in yellow. The stop codon (TAG) is indicated by an asterisk.
The percentage of sequence identity and similarity among fugu sod2 gene and human, mouse, zebrafish, medaka sod1 and sod2 gene. The dots and dashes in the alignment represent sequence identity and missing amino acids respectively.
Phylogenetic relationships between sod1 and sod2 sequence from fugu and sod sequences from other vertebrates. Accession numbers of the sequences used for phylogenetic tree are the following: Fugu Sod1/Sod2: HE602549, HE602550, Tetraodon Sod1/Sod2/Sod3: H3CX53, Q4S6V6, H3D497; Japanese medaka HDrR Sod1/Sod2: XP_004076261, GCA_002234675, Zebrafish Sod1/Sod2/Sod3: NP_571369, NP_956270, XP_001332758, Mouse Sod1/Sod2/Sod3: NP_035564, NP_038699.2, NP_035565, Human Sod1/Sod2/Sod3: NP_000445, NG_008729, NP_003093.
Conserved gene synteny of fugu sod genes.
