Optimum Conditions for Enhanced Production of Podophyllotoxin from Penicillium sp. Isolated from Khanspur, Pakistan
Umar Farooq Gohar, Attia Majeed, Bushra Muneer* and Hamid Mukhtar
Institute of Industrial Biotechnology, Government College University, Lahore, Pakistan 54000.
* Corresponding author: bushramuneer11@yahoo.co.uk, dr.bushramuneer@gcu.edu.pk
Fig. 1.
Phylogenetic tree of endophytic fungi Penicillium sp. P 18 isolated from Podophyllum hexandrum based on ITS region with top ten most similar sequences.
Fig. 2.
Physical parameters (A): incubation time; (B): Temperature; (C): pH and (D): inoculum size on the production of podophyllotoxin by Penicillium sp. P-18 using surface culture fermentation in YSB medium.
Fig. 3.
Effect of different concentrations of (A) Glucose, (B) Peptone, and (C) Ammonium phosphate on the production of podophyllotoxin by Penicillium sp. P-18 by using surface culture fermentation in YSB medium pH5.5 at 25°C.