Predictive Study of Serum Matrix Metalloproteinase-8 in Combination with Human Chorionic Gonadotropin in Preterm Amniotic Cavity Infection
Predictive Study of Serum Matrix Metalloproteinase-8 in Combination with Human Chorionic Gonadotropin in Preterm Amniotic Cavity Infection
Yashu Lv*, Yueyue Gao, Jinyi Wang, Yunchun Liu and Guiqing Jiao
ABSTRACT
The objective of this study was to investigate the predictive value of serum matrix metalloproteinase-8 (MMP-8) combined with human chorionic gonadotropin (hCG) for preterm amniotic cavity infection. The study included ninety patients with preterm labor admitted from June 2021 to October 2022 in the First Affiliated Hospital of Hebei North University, including the premature rupture of membranes group and the intact fetal membranes group. The same number of pregnant women with the same gestational age as in the experimental group were randomly selected as the study subjects in the outpatient clinic. Maternal sera from both groups β-hCG, MMP-8 levels were expressed and compared with those in the group with intra amniotic infection and no intra amniotic infection β- Higher levels of hCG, MMP-8 expression (P<0.05; Placentas from both groups β-hCG, MMP-8 levels were expressed and compared with those in the group with intra amniotic infection and no intra amniotic infection β- Higher levels of hCG, MMP-8 expression were factors associated with the development of preterm intra amniotic infection (P<0.05). It was concluded that in the serum of patients with preterm amniotic cavity infection, MMP-8 β- The values of hCG showed obvious expression by detecting MMP-8 β-hCG expression, which helps to predict the presence of intraamniotic infection, and especially for the prediction of subclinical intraamniotic infection is of high clinical significance. MMP-8 and β- The combined hCG test can provide clinical data support for clinicians to fully judge the prognosis of mother and child and to administer clinical interventions as early as possible, with high diagnostic efficacy.
To share on other social networks, click on any share button. What are these?
