Proliferation Capacity and Expression of Cell Cycle Genes in Normal and Gestational Diabetes Affected WJMSCs
Proliferation Capacity and Expression of Cell Cycle Genes in Normal and Gestational Diabetes Affected WJMSCs
Nabila Rasheed1, Shumaila Usman2*, Madeeha Sadiq3, Bushra Wasim3, Kanwal Haneef4, Hafsa Shafqat3, Tabinda Urooj3 and Saman Rashid4
Immunocytochemistry of WJMSCs CD90 protein (A) ACTIN (B) and protein showed positive expression for the WJMSCs in cord tissue.
Relative genes expression of cell division cycle genes (CDCA2, A8, A20, CCNA2), in control and GDM WJMSCs. There was a significant change in gene expression of two groups. As compared to control, GDM WJMSCs showed highly significant down regulation of cell cycle genes, which confirms the decreased proliferation rate in GDM WJMSCs.