Two Novel Missense Tbx22 Mutations Frequently Cause Non-Syndromic Cleft Palate in Pakistani Population
Two Novel Missense Tbx22 Mutations Frequently Cause Non-Syndromic Cleft Palate in Pakistani Population
Asma Basharat1, Abdul Wajid2*, Andleeb Batool1, Tayyeba Batool3, Abdul Basit4, Kamran Abbas5, Aziz Ullah1 and Mahmood Shaukat6
Fig. 1.
Chromatogram of a novel mutation A) C→A (P180Q) in the TBX22 gene, upper sequences of amino acids of unaffected individual and the lower of affected individual B) Patient images during surgery, C) G→T (S328I) in the TBX22 gene, the upper sequence belong to unaffected individual and below of affected individual.
Fig. 2.
Location of the novel missense substitutions, P180Q and S328I (red arrow), in the TBX22 gene.
February 2023
Vol. 55, Iss. 1, Pages 1-500
