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Antioxidant and Antidiabetic Potentials of Punica granatum Peel Extracts in Alloxan-Induced Diabetic Albino Rats

Antioxidant and Antidiabetic Potentials of Punica granatum Peel Extracts in Alloxan-Induced Diabetic Albino Rats

Aamir Khan Awan1, Nighat Sultana1*, Rahmat Ali Khan2, Rifhat Sultana3
Umm-e-Kalsoom1, Fayaz Ahmed Sahibzada4, Rifat Ullah Khan5, Naimat Ullah Khan6, Nazir Ahmad Khan7, Syed Haider Zaman8, Mir Sadiq Shah9 and Assar Ali Shah10*

1Department of Biochemistry, Hazara University, Mansehra, Khyber Pakhtunkhwa, Pakistan.
2Department of Biotechnology, University of Science and Technology, Bannu, Khyber Pakhtunkhwa Pakistan.
3Department of Chemistry, Hazara University Mansehra, Khyber Pakhtunkhwa, Pakistan.
4Department of Clinical Nutrition AIMS, Hospital, Muzaffarabad, Pakistan.
5College of Veterinary Science, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan.
6College of Veterinary Sciences and Animal Husbandry, Abdul Wali Khan University, Mardan, Pakistan.
7Department of Animal Nutrition, The University of Agriculture Peshawar, 25130, KP, Pakistan.
8Department of Clinical sciences, KBCMA, College of Veterinary and Animal sciences, Narowal sub-campus University of Veterinary and Animal sciences Lahore, Pakistan.
9Department of Zoology, University of Science and Technology, Bannu, Khyber Pakhtunkhwa, Pakistan.
10Tropical Feed Resources Research and Development Center (TROFREC), Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen 40002, Thailand.
 
*      Corresponding author: [email protected], [email protected]

Fig. 1.

Three different varieties of pomegranate.

Fig. 2.

DPPH scavenging activity of three varieties of P. granatum extracts in (A) Methanolic extract (B) Aqueous extract. The red, white and wild are three different varieties of pomegranate. Ascorbic acid (Vitamin C) was used as a standard (antioxidant). 

Fig. 3.

In-vitro antidiabetic activity (α-amylase inhibition) of three varieties of P. granatumin (A) Methanolic extract (B) Aqueous extract. The red, white and wild are three different varieties of pomegranate. Glucophase was used as antidiabetic standard.

Equation 1

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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