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Association of HLA DRB1 Alleles with Asthma in Pakistani Population of Punjab Region

Association of HLA DRB1 Alleles with Asthma in Pakistani Population of Punjab Region

Shehar Bano Bhatti1, Muhammad Irfan Malik2, Rabia Faryad Khan1, Mahmood Ul Hassan2, Muhammad Shahbaz Aslam3 and Zaigham Abbas1*

1Institute of Microbiology and Molecular Genetics, University of the Punjab, Quaid-e-Azam Campus, Lahore-54590, Pakistan
2Postgraduate Medical Institute, Lahore General Hospital, Lahore, Pakistan.
3Institute of Biochemistry and Biotechnology, University of the Punjab, Quaid-e-Azam Campus, Lahore-54590, Pakistan
 
*      Corresponding author: [email protected]

Fig. 1.

HLA Typing using SSP Primers: L, 50 base pair ladder, A: GAPDH (internal Control), B: different HLA DRB1 alleles. Lane 1: HLA DRB1* 0701-02, Lane 2: HLA DRB1* 1001, Lane 3: HLA DRB1* 1101-04, Lane 4: HLA DRB1* 1201-02, Lane 5: HLA DRB1* 1301-04.

Fig. 2.

Association of HLA DRB1 allele frequency with non-atopic (<150 IU/ml) asthma patients and atopic (>150 IU/ml) asthma patients.

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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