CDX1 Gene Expression in Recurrent Spontaneous Abortion under Extracellular Regulatory Protein Kinase1/2 Signaling Pathway
Shouyan Cao1, Aili Yan2, Wenhua Zhang3, Fangfang Li1 and Xiaoning Liu4*
1Department of Gynecology and Obstetrics, Binzhou Medical University Hospital, Binzhou, 256600, China
2Department of Gynecology, Gaomi Hospital of Traditional Chinese Medicine, Gaomi, 261500, China
3Department of Gynecology, Qingdao Central Hospital, Qingdao, 266042, China
4Department of Gynaecology and Obstetrics, Qingdao Women and Children’s Hospital, Qingdao, 266000, China
Fig. 1.
Frequency of CDX1 genotypes.
*shows there is a statistically substantial differencecompared with group A (P<0.05). Group A: Non-pcegnant healting female employees (control); Group B: Non-pregnant female patients.
Fig. 2.
Phosphorylation levels of ERK1/2 in subject from both groups.
* shows there is a statistically huge difference compared with group A (P<0.05).
See Figure 1 for details of groups.
Fig. 3.
CDX1 allele frequency in patients of group A (A), and group B (B).
See Figure 1 for details of groups.
Fig. 4.
Homocysteine and folic acid levels in subjects with the three genotypes.
* shows there is statistically marked differences in contrast to group A (P<0.05).
See Figure 1 for details of groups.
Fig. 6.
Comparison on abortion frequency of different genotypes.
* shows that the difference is statistically considerable in contrast to TT genotype in patients with less than 3 abortions (P<0.05).
Fig. 5.
Folic acid (A) and RR (B) of three genotypes in group B.
* shows there are statistically great differences in contrast to TT (A) and CC (B) genotype (P<0.05).
See Figure 1 for details of groups.